ABO
Rh
Other Blood Groups
Lewis
Apheresis
Blood Donors
200
N-Acetylgalactosamine is the terminal sugar for which ABO type?
Type A
200
Which Rh antigen is the most immunogenic
D antigen
200
Patients of African descent who are double Duffy negative are unlikely to form which Duffy antibody?
Anti-Fyb – Most patients of African descent have GATA box mutations in promoter region and make Fyb in other tissues but not on RBCs and therefore don’t typically form Anti-Fyb
200
Which precursor chain is present on red blood cells (Type 1 or 2)?
Type 2
200
What type venous access is needed for an apheresis procedure?
Double lumen catheter central line or a line in each antecubital fossa
200
Frequency of platelet donations
≤ 2/week, at least 2 days apart, ≤ 24 in a 12 month period
400
What is a cause of extra reactivity on the reverse type?
Anti-M or other cold reacting antibody
Anti-A1
Anti-CD47 antibody
400
Are Rh antigens destroyed or enhanced by enzymes?
Enhanced: Lewis is a PeeIing Rhotten Kidd
400
What are 3 antigens that are destroyed by enzymes?
Duffy
MNS
Lutheran
Chido
Rodgers
Duffy MeNS Lutheran ChoiR
400
The Le gene encodes this enzyme?
FUT3
400
For which disease is plasma the required replacement fluid (instead of albumin)?
TTP
400
The deferral for having received the chicken pox vaccine is?
4 weeks
Rubella (German measles) and varicella zoster (chicken pox) have 4 week deferrals
"Avoid German Chickens for 4 weeks"
600
This disease is associated with the acquired B phenomenon
Gram-negative bacteremia with intestinal obstruction and/or colon cancer
600
What is the calculation for determining the proper dose of RhIg
(Maternal blood volume x FMH) / 30
Round and add 1
600
Anti-P biphasic hemolysin antibodies seen in Paroxysmal Cold Hemoglobinuria (PCH) can be identified using this test?
Donath-Landsteiner
600
FUT2 gene is also known as
Se (Secretor gene)
600
What ion level is effected by the anticoagulant used in apheresis?
Calcium
Citrate chelates calcium and leads to hypocalcemia
600
The deferral for having traveled to a malaria endemic region is?
3 months
800
This blood group has the least quantity of exposed H antigen?
Group A1B
800
Which two Rh haplotypes contain the f antigen?
r - dce
R0 - Dce
800
Antibodies to this blood group system are notorious for decreasing to undetectable levels and also for showing dosage?
Kidd
800
People who express Le(b) but not Le(a) on their RBCs and secretions have which genes?
Se and Le
800
Which medication class needs to be held for 24-48 hours before an apheresis procedure?
ACE inhibitors
Can cause hypotension, bradycardia, and dyspnea
800
Name 4 diseases that are tested for in all blood donations
HIV
HCV
HBV
Syphilis
HTLA-I/II
Chagas Disease (Trypanosoma cruzi)
West Nile
Babesia (regional)
1000
What gene encodes for the H antigen and is absent in a patient with Bombay phenotype?
FUT1
1000
Anti-G looks the same as a combination of which two antibodies?
Anti-D and anti-C
1000
What is the cell surface function of the Kidd Antigen?
Urea transporter
1000
A person has the genotype Hh, sese, and Lele. What antigens will his/her red cells demonstrate?
H, Le(a)
1000
What type of apheresis procedure is done for familial hypercholesterolemia?
LDL or Lipid Apheresis
1000
Minimum hemoglobin levels to donate
≥13.0 g/dL (male); ≥12.5 g/dL (female)