Lectins/Neutralizing Agents
Antibody Identification
Transfusion Reactions
Component Therapy
Platelet Refractoriness
Blood Bank Numbers
Final Jeopardy
400
This lectin binds to the H antigen
Ulex europeaus
400
Reagent cell 3 on an antibody screen is always which Rh haplotype
r/r
400
What reaction presents with fever, flank pain, and hemoglobinuria? Onset typically within 15 minutes
Acute hemolytic transfusion reaction
400
What is the standard hemoglobin threshold for a RBC transfusion?
<7 g/dL
400
A platelet transfusion is expected to increase a patient's count by how much?
20-50K
400
Expiration of RBCs with CDP, CPDA, AS?
21 days
35 days
42 days
800
Group A1 and A2 red cells can be distinguished by used of this lectin
Dolichos biflorus
800
Daratumumab interference is removed by treating the reagent cells with what?
DTT (Dithiothreitol)
800
Which tests must the blood bank run to rule out acute hemolytic transfusion reactions?
DAT, visible hemolysis check
800
What is the strongest indication for transfusing plasma?
Trauma patients
800
This blood product modification decreases the frequency of HLA alloimmunization.
Leukoreduction
800
Dose of irradation to the center of the unit
25 Gray (2500 rad or 25 centigray)
15 to any point
1200
This antibody that causes mixed field agglutination resembling refractile copper pennies can be neutralized with guinea pig urine?
anti-Sd(a)
1200
A weakly reacting panreactive panel (1+) with a negative autocontrol is an indication of what type of antibody?
High Titer Low Avidity (HTLA)
Examples include: Chido/Rogers (Ch/Rg), Sda, Cartwright, John Milton Hagen (JMH)
1200
Which reaction leads to the highest number of fatalities?
TACO
1200
What is a proper dose of cryo for an adult?
1 pool of five
1200
What would you recommend for a patient with an increment of only 10K, but a CCI of 15,000?
Transfuse multiple units. Likely a large BSA. Do not need HLA matched
1200
Success rate required on ABO testing on Proficiency Testing
100% (mostly everything else only requires 80%)
1600
This lectin binds to the B antigen?
Bandeiraea simplicifolia
1600
A mixture or different strengths of reactivity on a panel is an indication of what?
Multiple antibodies and/or the dosage effect
1600
Irradiation is done to prevent which transfusion reaction?
Transfusion-associated graft vs. host disease
1600
What is the threshold for platelet transfusion if the patient is going for neurosurgery?
100 K
1600
What does the PRA mean?
Panel reactive antigens
Percentage of random donors who would be incompatible
1600
Amount of WBC lefts after leukoreduction
5 x 106
1600
Who discovered the ABO Bood Groups and in what year?
Karl Landsteiner in 1901
2000
Which substance can neutralize anti-I?
Breast milk
2000
The rare X-linked Chronic Granulomatous Disease is associated with this unusual red cell phenotype?
The McCleod phenotype (Kell null with weak k, Kpb & Jsb)
2000
What TRALI mitigation strategy is used in the USA (and many other countries)?
Male only plasma
2000
What premedications should a donor receive if they are going to donate granulocytes to get an effective dose?
Steroids and G-CSF
2000
What are the variables in calculating a corrected count increment (CCI)?
Platelet increment
Body Surface Area
Number of platelets transfused
2000
Minimum concentration of fibrinogen in a cryo unit?
150 mg
2000
What 2 Disney Legos does Dr. Harrold have on the top of the cabinets in his office?
Steamboat Willie
Oswald the Lucky Rabbit
