Law
A whole lot of what is known about adverse drug side effects is pulled from _____ reports.
A) Concurrent pharmacy
B) Concurrent marketing
C) Postmarketing
D) Postpharmacy
C) Postmarketing
A) Modulate neuronal sodium channels
B) Modulate neuronal calcium channels
C) Enhance GABA transmission
D) Enhance glutamate transmission
D) Enhance glutamate transmission
[inhibit NOT enhance]
[Immun] Pharmacists are included in the immunization process to help ____.
A) The community stay healthy
B) Reduce the burden of the clerks at the store
C) Prevent the use of vaccinations
D) Customers buy more goods.
A) The community stay healthy
Which of the following chemotherapy agents is a the pro-drug of 5-fluorouracil?
A) Oxaliplatin
B) Bleomycin
C) Vinblastine
D) Capecitabine
D) Capecitabine
Which of the following antibiotics should be avoided in a patient with a penicillin allergy (anaphylatic shock)?
A) Cefoxitin
B) Minocycline
C) Azithromycin
D) Levofloxacin
A) Cefoxitin
What kind of error is it considered when a pharmacist gives a patient the wrong medication?
A) Adverse drug effect
B) Missed dose
C) Allergy
D) Dispensing error
D) Dispensing error
[Psych - ADHD] Which of the following alpha2-agonists is sometimes used as adjunc therapy for ADHD?
A) Brimonidine
B) Guanfacine
C) Methyldopa
D) Tizanidine
B) Guanfacine
[Immun] A child, PO, is on track for his vaccination schedule (complete through 5yo). He has just turned 6yo and presents to his pediatricians for well-child check up and immunizations. What immunizations is PO due for at this visit?
A) Hepatitis B, DTap, PCV
B) DTap, Varicella, Rotavirus
C) Varicella, DTap, Inactivated Polio, MMR
D) Tdap, HPV, Meningococcal
C) Varicella, DTap, Inactivated Polio, MMR
Adequate hydration and mesna therapy are recommended when using which of the following alkylating agents?
A) Carmustine
B) Ifosfamide
C) Busulfan
D) Temozolomide
B) Ifosfamide
(to prevent bladder toxicity)
All but which of the following antibiotics inhibit bacterial cell wall synthesis?
A) Amoxicillin
B) Gentamicin
C) Cephalexin
D) Meropenem
B) Gentamicin
Adverse drug effects can be reported through the _____.
A) FDA Adverse Event Reporting System (FAERS)
B) Adverse Drug Effects System for Pharmacists (ADESP)
C) Bad Drug Database System
D) FDA Adverse Drug Evaluation System (FADES)
A) FAERS
[Cardio] Which of the following groups of medications decrease both preload and afterload?
A. ACE inhibitors, diuretics and B-blockers
B. ACE inhibitors, Natrecor, and nitrates
C. Hydralazine, INocor and CCBs
D. B-blockers and CCBs
B. ACE inhibitors, Natrecor, and nitrates
[DM] All but which of the following medications can cause hypoglycemia?
A) Glucophage
B) Glucotrol
C) Starlix
D) Glynase
A) Glucophage
Which of the following chemotherapy agents is a tyrosine kinase inhibitor?
A) Vinorelbine
B) Doxorubicin
C) Imatinib
D) Goserelin
C) Imatinib
Which of the following is contraindicated in neonates?
A) Ceftriaxone
B) Cefotaxime
C) Oxacillin
D) Gentamicin
A) Ceftriaxone
If a controlled substance does not require a prescription, where can a pharmacist store it?
A) Behind the counter or in a locked case in the aisles
B) Behind the counter only
C) In a locked case in the aisle only
D) There are no placement restrictions
A) Behind the counter or in a locked case in the aisles
[Cardio CHF] D.H. is a 72-year-old male with a past medical history of hypertension, DM type 2 and NYHA class III systolic heart failure.
Medications:
Lisinopril 10 mg PO QD
Coreg 6.25 mg PO BID
Glyburide 2.5 mg PO QD
Lasix 40 mg PO BID
Eplerenone 25 mg PO QD
Aspirin 81 mg PO QD
Nitroglycerin PRN
Vitals: BP: 115/72 mmHg Pulse: 84 Resp: 16 Temp: 98.6 O2 sat: 96%
Labs:
SCr .................. 1.1 mg/dL
K+ ................... 4.3 mEq/L
What is the mechanism of action and the primary role of eplerenone in the treatment of heart failure for this patient?
A. Aldosterone antagonist to modulate the diuretic effect of loops in CHF
B. Aldosterone antagonist to control potassium level in CHF
C. Aldosterone antagonist to reduce morbidity and mortality in CHF
D. Aldosterone antagonist for the treatment of acute decompensated pulmonary edema.
C. Aldosterone antagonist to reduce morbidity and mortality in CHF
[DM] Which of the following insulins has the shortest duration?
A) Glulisine
B) Detemir
C) Regular
D) Glargine
A) Glulisine
[[DJ!!!]] Which of the following chemotherapy agents is FATAL if administered intrathecally?
A) Docetaxel
B) Vincristine
C) Oxaliplatin
D) Cyclophosphamide
B) Vincristine
Which of the following regimens is the most appropriate to use for treatment of a severe Clostridium difficile infection?
A) IV metronidazole
B) PO Vancomycin & PO metronidazole
C) IV Vancomycin & IV metronidazole
D) PO vancomycin & IV metronidazole
D) PO vancomycin & IV metronidazole
What are 2 reasons why proper medication packaging is important?
A) To maintain the quality of the medication & to reimburse insurance costs
B) To provide easy access to medication & to protect medication from contamination
C) To correctly identify medication & to keep medication from being damaged
D) To provide individual doses of medication & to ensure the correct quantity of medication
C) To correctly identify medication & to keep medication from being damaged
DJ!!! [Cardio - CHF] WC is a 67-year-old man with HTN, hyperlipidemia, and CAD, and had triple bypass surgery 17 years ago. He presents to the clinic with shortness of breath (SOB), which occurs when performing simple tasks such as sweeping the floor. He reports sleeping in a recliner at night due to orthopnea. Physical examination reveals elevated jugular venous pressure and 1+ pitting lower extremity edema (LEE).
Home medications: amlodipine 10 mg QD, atorvastatin 80 mg QD, and aspirin 81 mg QD
ECG: demonstrates systolic dysfunction, mild mitral regurgitation, a dilated left atrium, and an ejection fraction (EF) of 30%.
Lab: pro-B-type natriuretic peptide level of 1302 pg/mL, a troponin level of <0.34, basic metabolic panel (BMP): WNL
Vital signs: BP 156/92 mm Hg, HR 80 beats/min, SpO2 of 94%, T: 36.5 °C, pain level of 2 on a scale of 10, Wt 185 lb (84.1 kg)
What is WC's New York Heart Association (NYHA) functional classification of Heart Failure?
A) NYHA Class IV
B) NYHA Class III
C) NYHA Class II
D) NYHA Class I
C) NYHA Class II
(patient has SOB with normal activity, but is comfortable at rest)
[DM] HJ is a 21yo F who presents to the ED today with severe stomach pain, nausea, vomiting, fatigue and increased urination for 2 days
Dx: T1DM, GAD
Medications:
Apidra Solostar 3 units AC meals
Lantus Solostar 15 units QHS
Ativan 1mg BID
Vitals: BP: 115/72 mmHg Pulse: 84 Resp: 16 Temp: 98.6 O2 sat: 96%
Labs:
Na .................. 139 mEq/dL
K+ ................... 4.5 mEq/L
Glucose..............593 mg/dL
Urine ketones......Positive (++)
Which of the following is the most likely diagnosis for HJ?
A) Sepsis
B) Diabetic ketoacidosis
C) Hyperglycemia hyperosmolar state
E) Insulin overdose
B) Diabetic ketoacidosis (DKA)
A pt with end stage breast cancer has been experiencing fatique & dehydration. She has a corrected calcium of 11.5mg/dL. What is most appropriate for treating her hypercalcemia?
A) Instruct pt to drink 8 glasses of water
B) IV hydration, loop diuretic & zoledronic acid
C) Calcitonin
D) Vitamin D
B) IV hydration, loop diuretic & zoledronic acid
[[DJ!!!]] PM is a 44yo M being seen in the GI clinic for follow up. He was recently diagnosed with HCV & expected to start treatment this week with Harvoni. His PMH is significant for depression & GERD. PM stopped using alcohol & IV drugs 5 years ago. He has repeatedly tested negative for HIV over many years.
Allg: NKDA
Meds: Celexa 40mg QD, Pepcid 20mg QD, Tums 1-2 tabs PRN heartburn
Upon review of PM's medication list, which medication/s pose a potential drug-drug interaction risk with Harvoni?
A) Celexa
B) Pepcid
C) Tums
D) Tums & Pepcid
D) Tums & Pepcid