Hep A
Route of transmission
Fecal-oral
Name 3 categories of at risk individuals for Hep B
Foreign born, HBV Contact, IVDU, SDI, MSM, incarceration, Hep C or HIV, ESRD-HD, pregnancy
+HCV Antibody test should be followed up by which testings?
HCV RNA Quantification with reflex to genotype
Hepatitis B
Current USPSTF recommendation for Hep C screening
All adults aged 18-79 yo (Grade B)
What is the diagnostic testing for Acute Hep A
IgM antibodies to HAV
This phase of Hep B infection can only be acquired from birth (vertical transmission)
Immune Tolerant
+Hep C patient should be tested for these 2 other viral illnesses
HIV & Hep B
This virus required Hep B coinfection as vector
Hepatitis D
This lab value is most specific for liver injury
AST (Aspartate aminotransferase)
What does (+) IgG antibodies to HAV mean?
Previous infection or immunization
What is the "window" period during Hep B Infection?
Time between disappearance of HBsAg and before HBsAB is detected
Which Hep C genotype is the most common?
Genotype 1 (a & b), there are 6 total genotypes
This viral hepatitis is common among organ-transplant recipient
CMV Hepatitis
What HCC screening modalities and intervals are recommended for patients with Hep B/Hep C?
Abdominal US every 6 mo, or Helical CT or MRI
What is the CDC recommended vaccination schedule for Hep A?
Children > 1 yo, 2 doses, 6 months apart (Havrix and Vaqta)
Identify this infection:
HBsAG (+); Anti-HBs (-); Anti-HBc (+) IgG; HBeAg (-)
Inactive chronic Hep B
Name a treatment regimen for Hep C genotype 1a
Ledipasvir-sofosbuvir
Velpatasvir-sofosbuvir
Glecaprevir-pibrentasvir
These 2 viral hepatitis can cause fulminant liver failure in pregnant women during 3rd trimester
Hepatitis E & HSV hepatitis
% of acute Hep C becoming chronic Hep C
70-80%
This is a form of Hep A that has a recurrent feature after spontaneous viral clearance.
Relapsing, remitting infection with cholestatic feature
Entecavir or Tenofovir or pegylated interferon
This vasculitis disease is strongly associated with Hep C
Mixed cryoglobulinemia
Small vessel vasculitis with glomerulonephritis
Porphyria cutanea tarda
Pegylated interferon
This skin manifestation is associated with Hep B infection
Polyarteritis nodosa