EGDT
Amount of IV fluid needed
30 ml/kg
Type of fluid used for fluid bolus
Isotonic (LR or NS)
Causes intravascular dehydration
Capillary leak
Increase
HR x SV
Cardiac output
Do not delay antibiotics to obtain
Cultures- Blood cultures
type of drug to increase cardiac contractility
inotrope
Produced secondary to tissue hypo perfusion
lactate
Platelet count
Decrease
resistance to blood flow in the vascular system
SVR Systemic Vascular resistance
pan culture
Type of antibiotics given early in sepsis
Broad Spectrum or Empiric ABx
dysregulated immune response that causes vasodilation and capillary leak
cytokine storm
Fibrinogen
Decreased
Normal pressure in the PA artery
25/10
Passive leg raise increases blood pressure MAP by 10 mmHg
Give more fluid
vasopressor of choice for hypotension
Norepinephrine (Levophed)
First vital sign to be abnormal
Resp. rate
Clotting time
Increase
Name for pressure in Right atrium/distal superior vena cava
CVP central venous pressure
EGDT therapy is working when repeat lactate decreases
10%
Inotrope used first line in sepsis
Dobutamine
The leakage of this substance in alveoli leads to acute respiratory distress syndrome and decreased lung compliance
Surfactant
D-Dimer does this
increases
Left ventricular end dystolic pressure/volume
Preload