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Maths
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Final Jeopardy
100

The USPSTF recommends 1-time screening for abdominal aortic aneurysm (AAA) with ultrasonography in men aged 65 to 75 years.

The USPSTF recommends 1-time screening for abdominal aortic aneurysm (AAA) with ultrasonography in men aged 65 to 75 years who have ever smoked

100

 in 2011, 80,000 people were tested for diabetes in Town A. Of those tested, 9,000 were found to have diabetes and 71,000 tested negative. What is the prevalence of diabetes in Town A in 2011?

11%

Prevalence = number of individuals with a disease at a given point / population at risk for the disease at that point in time

9,000/80,000

100

Anterior appendix

Tip of the Right 12th rib

100

A 5 year-old boy presents to the clinic with a 3-week history of sinus drainage and congestion. He awoke this morning with a fever, left eyelid swelling, painful left eye movements, and vision changes. He reports no headache and his parents have not noticed any mental status changes. Temp is 39.3*C. Exam reveals edema and erythema over the left upper and lower eyelid with mild proptosis. What is the most likely diagnosis

Orbital Cellulitis 

Tx vancomycin plus piperacillin-tazobactam, ceftriaxone, cefotaxime, or ampicillin-sulbactam

100

πŸŽˆπŸ‘΄πŸ 

Up


200

The USPSTF recommends annual screening for lung cancer with low-dose computed tomography (LDCT) in adults aged 50 to 80 years who have a 15 pack-year smoking history and currently smoke or have quit within the past 20 years. Screening should be discontinued once a person has not smoked for 20 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery.

The USPSTF recommends annual screening for lung cancer with low-dose computed tomography (LDCT) in adults aged 50 to 80 years who have a 20 pack-year smoking history and currently smoke or have quit within the past 15 years. Screening should be discontinued once a person has not smoked for 15 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery.

200

The performance of a new diagnostic test for H. pylori is being evaluated in a population of 1,000 individuals of which 200 have the disease. Results show 100 true positives, 100 false positives, 100 false negatives, and 700 true negatives. What is the positive predictive value?

50%

PPV is the chance a person with a positive test truly has the disease

PPV = True positives/total positives


200

Inferior to the medial aspect of the clavicles

Sinuses

200
A 65 y/o man presents to the clinic with vision loss in his right eye that occurred over 10-15 minutes today. He reports no pain, fever, or headache. PMHx includes poorly controlled diabetes and HLD with a 20 pack-year smoking history. Penlight exam shows a relative afferent pupillary defect of the right eye. Ophthalmoscopic exam shows a cherry red spot and retinal whitening. He has mild scalp tenderness to the right temple. What is the most likely diagnosis. 

Central retinal artery occlusion

200

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Men in Black 

300

The USPSTF recommends that clinicians prescribe a statin for the primary prevention of CVD for adults aged 40 to 75 years who have 1 or more CVD risk factors (i.e. dyslipidemia, diabetes, hypertension, or smoking) and an estimated 10-year risk of a cardiovascular event of 5% or greater.

The USPSTF recommends that clinicians prescribe a statin for the primary prevention of CVD for adults aged 40 to 75 years who have 1 or more CVD risk factors (i.e. dyslipidemia, diabetes, hypertension, or smoking) and an estimated 10-year risk of a cardiovascular event of 10% or greater.

300

A new screening test for lung cancer is being studied to assess its effects on the five-year mortality rate of individuals who have smoke cigarettes for at least 25 years. The results show that the mortality of the unscreened group is 200/1000 and the screened group is 100/1000. What is the absolute risk reduction of the new screening test?

10%

ARR is an estimate of the risk of an event for a patient undergoing intervention or screening compared to without the intervention or screening

ARR = event rate in control - event rate in intervention group

0.2-0.1 = 0.1 = 10%


300

Anterior adrenals

2" superior and 1" lateral to the umbilicus

300

A 67 y/o woman presents to the clinic with a 5 day history of vision changes in her right eye. PMHx includes diabetes, HTN, HLD, and a 40 pack/year tobacco use history. She reports difficulty reading and straight lines appear curvy. Amsler grid tool is positive on the right. What is the most likely diagnosis?

Wet/Exudative age-related macular degeneration 

300

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Forest Gump

400

The USPSTF recommends that women at average risk for breast cancer start yearly mammograms at age 45, with the option to begin at age 40. Women 55 and older should switch to mammograms every 2 years, or can continue yearly screening. Screening should continue as long as a woman is in good health and is expected to live 10 more years or longer.

This is the American Cancer Society (ACS) recommendation 

The USPSTF recommends biennial screening mammography for women aged 40 to 74 years.

400

A study evaluates the benefits of fecal occult blood testing for detecting colon cancer. Of the 100 people in the study, 80 had a negative test and 20 had a positive test. Of the 80 with a negative test, 10 had colon cancer. Of the 20 with a positive test, 5 had colon cancer. What was the sensitivity of the test?

33%

Sensitivity is the probability of a positive result in a patient that truly has the disease. ie the ability to identify true positives

 Sensitivity = True positives / total number of people with disease

5/(10+5)=33%

400

Between ribs 2 and 3 at the sternocostal junction on the right 

Heart

400

A 30 y/o woman presents with a three-day history of left eye pain associated with eye movement and vision changes. Exam reveals a left-sided visual field loss consistent with central scotoma and a sluggish pupilar response to direct light on the left and normal response on the right. What imaging modality would confirm the most likely diagnosis?

MRI brain and orbits with contrast (Optic neuritis)

400

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Legally Blonde

500

In adults with hypertension without clinical CVD and with estimated 10-year CVD risk <7.5% based on ASCVD, initiation of medications to lower BP is recommended if average SBP remains β‰₯130 mm Hg or average DBP remains β‰₯80 mm Hg after a 3- to 6-month trial of lifestyle intervention to prevent target organ damage and mitigate further increases in BP.

In adults with hypertension without clinical CVD and with estimated 10-year CVD risk <7.5% based on PREVENT, initiation of medications to lower BP is recommended if average SBP remains β‰₯130 mm Hg or average DBP remains β‰₯80 mm Hg after a 3- to 6-month trial of lifestyle intervention to prevent target organ damage and mitigate further increases in BP.

500

A company is assessing the link between exposures to two different chemicals and the risk of developing a stroke. They have two chemical plants each with 50 employees. The first plant uses chemical A and 9 employees had a stroke. The second plant switched to using chemical B and 3 employees had a stroke. What is the relative risk reduction of switching to chemical B?

67%

RRR is the relative decrease in risk of a disease or adverse event in the intervention group compared to the control group

RRR = (control group risk - intervention group risk)/control group risk

(0.18-0.06)/0.18 = 67%

500

Stomach (mobility)

Ribs 6 and 7 on the left 

500

A 65 y/o woman presents to the office with acute onset blurred vision and pain in her right eye. She reports seeing halos around lights. Exam shows a dilated right pupil, a red eye, and corneal cloudiness. Her current medication list includes lisinopril, amlodipine, amitriptyline, metformin, hydroxyzine, levothyroxine, and fluticasone nasal spray.  Which medication(s) may have contributed to her condition?

Amitriptyline and hydroxyzine 

Antihistamines, asthma medications, adrenergic, anticholinergics, and tricyclic antidepressants can all worsen/precipitate acute angle-closure glaucoma

500

🌽🌍😱   πŸ§‘β€πŸš€    πŸŒŠπŸŒŒβ°  πŸ”₯🌽   πŸ‘©πŸ“šπŸ‘Œ 

Interstellar

500

Give 3 of 4 American Diabetes Association Diagnostic Criteria for Diabetes Mellitus


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