Around the Pharmacy
What is Clint's sister's name
Kalyn Kramer
Which beta-lactam is generally preferred for serious infections caused by ESBL-producing Enterobacterales outside of the urinary tract?
A carbapenem such as meropenem
This vasopressor is generally recommended as the first-line vasopressor for septic shock.
Norepinephrine
Lisdexamfetamine
Vyvanse
Which anticoagulant is preferred during pregnancy when therapeutic anticoagulation is required?
Low-molecular-weight heparin
What is John's youngest son's name
Ben
A patient taking linezolid develops thrombocytopenia after prolonged therapy. Which monitoring parameter should the pharmacist prioritize?
CBC/platelet count
A patient on norepinephrine remains hypotensive despite escalating doses. Which vasopressor is commonly added rather than simply continuing to escalate norepinephrine indefinitely?
Vasopressin
Budesonide + Formoterol
Symbicort
A patient on unfractionated heparin develops a platelet decrease >50% approximately one week after initiation. What dangerous complication should be considered?
Heparin-induced thrombocytopenia (HIT).
What's Jessica's favorite color
Purple
A patient with MSSA bacteremia is receiving vancomycin. Cultures show MSSA and there is no severe beta-lactam allergy. What should the pharmacist recommend?
De-escalate to an anti-staphylococcal beta-lactam, such as nafcillin/oxacillin or cefazolin.
A patient with septic shock remains hypotensive despite adequate fluids and vasopressors. Which corticosteroid regimen is commonly used?
Hydrocortisone 200 mg/day
Tiotropium
Spiriva
A patient has suspected HIT. What should happen to heparin therapy?
Stop all heparin products and initiate an appropriate non-heparin anticoagulant when clinically indicated.
4' 8.5"
What drug class is this MOA:
DNA gyrase inhibitor, and also inhibits topoisomerase IV
Fluoroquinolones
A mechanically ventilated patient is deeply sedated with propofol. They develop metabolic acidosis, rhabdomyolysis, hyperkalemia, and cardiovascular instability. What rare but potentially fatal syndrome should be suspected?
Propofol infusion syndrome
Sitagliptin + Metformin
Janumet
A patient taking dabigatran develops life-threatening bleeding. What specific reversal agent is available?
Idarucizumab
What is Chad's Mother-in-law's name?
Nancy Willis Pierce
A critically ill patient has MRSA bacteremia and receives vancomycin. The pharmacist recommends AUC-guided monitoring rather than trough-only monitoring. What AUC24/MIC target is generally recommended for serious MRSA infections?
AUC24/MIC of 400–600
A patient with severe symptomatic hyponatremia develops seizures. Hypertonic saline is indicated. What is the major pharmacologic concern during correction?
Overly rapid correction causing osmotic demyelination syndrome.
Efavirenz + Emtricitabine + Tenofovir
Atripla
A patient with mechanical mitral valve replacement asks whether apixaban can replace warfarin. What is the pharmacist's answer?
No. Warfarin remains the recommended anticoagulant; DOACs are not appropriate for mechanical prosthetic valves.