Geography
Art
Science
History
Mystery
100
Name the 7 continents
Asia, Africa, North America, South America, Antarctica, Europe, and Australia
100
Painted the Mona Lisa
Leonardo da Vinci
100
3 states of matter
Liquid Solid and Gas
100
Year WWI started
1914
100
HTML stands for
Hypertext Markup Language
200
Longest river in the world
Amazon river
200
Found on musical scores
Treble clef
200
The heart is in which body system
cardiovascular system
200
Year Declaration of Independence signed
1776
200
Year of the 1st Spider-Man movie
1977
300
The 4 of the 7 wonders of the world
Taj Mahal, the Colosseum, the Chechen Itza, Machu Picchu, Christ the Redeemer, Petra, and the Great Wall of China.
300
City this work of art (Girl with the Pearl Earring) can be found 
The Hague
300
Number of elements on the periodic table
118 elements
300
The number of presidents assassinated
Four
300
Name of Garfield's human from the Garfield Comics
Jon
400
Capital of Luxembourg
Luxembourg
400
The era the Sistine Chapel was painted
Renaissance
400
The neutral number on the PH scale
7
400
17th President of the US
Andrew Johnson
400
Dr. Seuss real name
Theodor Seuss Geisel
500
Name the 7 central American countries
Panama, Costa Rica, Nicaragua, Honduras, El Salvador, Guatemala, and Belize
500
First backstreet boys album
Backstreet Boys
500
Name this moon stage
Waning gibbous
500
Length of the Cold War
45 years
500
Century the 1st toilet was made
16th century