MoA
Change or Keep
Spectrum
Making Problems
Two Answers Min
100
General catergory of antibiotics that work by preventing bacterial cell wall synthesis by binding penicillin-binding proteins.
Beta Lactams
100
33 year old female with Pyelonephritis,
On Zosyn.
Urine culture growing >100,000 CU of GNB - Fermenter.
Deescalate or Keep?
Deescalate
100
This penicillin has antipseudomonal activity
Zosyn (PipTazo)
100
You prescribe your buddy Azithromycin for a URTI, most likely side effect?
DIARRHEA
100
Oral antipseudomonal. One Class.
Cipro or Levaquin
200
These antibiotics inhibit bacterial protein synthesis by binding the 30S ribosomal subunit.
Aminoglycosides or Tetracyclines
200
50 year old with diarrhea, watery, after eating Taco Bell lettuce. On Ceftin and Flagyl. Cyclospora is endemic.
DC and start Bactrim.
200
Cephalosporin w/ MRSA coverage
Ceftaroline
200
Broad spectrum Cephalosporin associated w/ AMS
Cefepime
200
IV ESBL Coverage
Carbapenems
Leva or Ciprofloxacin
Gentamicin
300
Beta Lactam class that can work on ESBL?
Carbapenems
300
55 year old male admitted with cellulitis, empirically on Vanco and Zosyn. Blood cultures grow back positive GPC in Clusters.
What are you doing Next?
DC Zosyn.
300
Beta Lactam - BUT ONLY GRAM NEGATIVE COVERAGE
Aztreonam
300
Treating a 25 year old female for H Pylori who is sexually active, and wants to get pregnant. What's the antibiotic you want to avoid AT ALL COSTS?
Tetracycline + Clarithromycin based
300
32 year old male with IVDU. Huge abscess.
Bactrim
Doxy
Zyvox
400
Term used to describe an antibiotic that prevents replication
Bacterostatic
400
60 year old with ESBL Ecoli bacteremia insistent on going home -- agreeable to IV antibiotics at home. NO PO options? Is on Merrem q8 hours.
DC and start Ertapenem.
400
IV Carbapenem without PSEUDOMONAL coverage?
Ertapenem
400
Patient admitted with a UTI, started on Ceftin. Next morning labs are abnormal, which labs?
LFTs
400
I need atypical coverage but can't use Azithro
3+ Gen Fluoroquinolone
Doxy
500
First truly synthetic antibiotic class?
Floroquinolones
500
76 year old male diabetic with acalcular choleycstitis. On Cefepime.
Growing Bacteroides.
What are you to do next?
Add anaerobic coverage (maybe double).
500
Covers GP, GN, Atypicals and Anaerobes... but mainly in the Lung
Moxifloxacin
500
Patient on Vanco. What do you do?
Slow the infusion rate
500
Two Oral Drugs to cover EFec
Amox or Amox/Clauv
Linezolid