Benzo's
Benzo Endings and Examples? Uses?
End in "LAM" and "PAM"
~ Diazepam (Valium)
~ Alprazolam (Xanax)
~ Chlordiazepoxide (Librium)
~ Lorazepam (Ativan)
- Anxiety, insomnia, seizures, alcohol withdrawal, pre-op
What to monitor on Benzo's?
Monitor LFT's, kidney fucntion, CBC, and UA
Benzo's are very ___ so potential fall risk
SEDATING
* PAM takes LorazePAM for her ANXIETY. She does not drive her BENZ anymore due to her BENZOS making her sedated. *
What is the most common Non-Benzo?
Buspirone (Buspar)
- THE BUS IS SLOW
Non-Benzo: Uses?
Used for Generalized anxiety disorder, panic disorder, OCD, and PTS
Benzo MOA?
Increases GABA (Grandma keeps everyone calm and relaxed)
Can you take Benzo's pregnant?
NO PREGNANCY
Max effects with Benzo's make take how long?
1-2 weeks
Non-Benzo Withdrawl Symptoms? What is the Antidote for Non-Benzo's?
NONE
NO ANTIDOTE
Non-Benzo's take a very long time to start working (T/F)
True
- Several weeks, longer than Benzo's
Benzo antidote?
Flumazenil
Do not ___ dose and you never ___ abruptly
- Don’t skip doses
- Taper on and off: NEVER abruptly stop
Do Benzo's or Non-Benzo's work faster?
Benzos
Non-Benzo: NO what?
Grapefruit juice
Non-Benzo's SE's?
SE: Dizziness, HA, nausea
NOOO>> Highly addictive: Should not be prescribed long term
Benzo's: Avoid what herb?
Avoid Valerian root
How long does tolerance take to develop on Benzo's?
6-8 weeks
Taking Non-Benzo's and ___ increase risk for serotonin syndrome.. you must have a __ week __ between them
SSRI's .. you must have a 2 week washout between switching drugs (give muscle relaxants)
- Caused by too much serotonin (which regulates sleep, mood, appetite, pain, and temp
- Serotonin is HIGH in anxiety and LOW in depressiOn
Can you use Non-Benzo's long term? WHY?
Yes can be used long term because they are NOT SEDATING
Benzo withdrawl symptoms?
Agitation, nervousness, insomnia, tremor, muscle cramps, sweating
Avoid?
OTC drugs and Alcohol
Do Non-Benzo's have lower or higher abuse potential?
Lower abuse potential with NON-Benzos