Lectins/Neutralizing Agents
Antigens
Transfusion Reactions
Component Therapy
ID Screening
Apheresis
Final Jeopardy
400
This lectin binds to the H antigen
Ulex europeaus
400
This antigen is a receptor for H. pylori?
Le(b)
400
Which tests must the blood bank run to rule out acute hemolytic transfusion reactions?
DAT, visible hemolysis check
400
What is the desired platelet count for surgeries?
50 k/uL
400
Which disease is screened for in blood donors in only select US states?
Babesia
400
What is the most common replacement fluid for a TPE?
Albumin
800
Group A1 and A2 red cells can be distinguished by used of this lectin
Dolichos biflorus
800
What is considered a critical titer for the K antigen?
4
800
This uncommon transfusion reaction is due to the anticoagulant used in RBC units.
Citrate toxicity
800
An apheresis platelet must contain at least # platelets?
3 x10^11
800
Which diseases found in a blood donor require a lookback at previous donations and notification to blood recipients?
HIV, HCV
800
What does a category III indication mean?
Optimum role of apheresis therapy is not
established. Decision-making should be
individualized.
1200
This lectin binds to the B antigen
Bandeiraea simplicifolia
1200
Red blood cells that are resistant to lysis by urea may be negative for these antigens.
Kidd antigens
1200
A donor implicated in this TR is deferred indefinitely?
Transfusion Related Acute Lung Injury (TRALI)
1200
What is the required percentage correct on PT testing for ABO typing?
100%
1200
What is the window period for HIV?
~9 Days
1200
What is the most common indication for extracorporeal photopheresis (ECP)?
Cutaneous T-cell Lymphoma
1600
This antibody that causes mixed field agglutination resembling refractile copper pennies can be neutralized with guinea pig urine
Anti-Sd(a)
1600
This antigen is expressed more strongly on D-positive cells and antibodies against it can cause confusion with anti-D?
Anti-LW
Landsteiner-Weiner
1600
What is the most common cause of fatalities from transfusion reactions currently?
Transfusion Associated Circulatory Overload (TACO)
1600
What is the best treatment for reversing warfarin?
Vitamin K or PCC
Not plasma
1600
Which has the highest theoretical risk of transmission? HIV, HBV, HCV?
HBV
Largest window period
1600
Which medication class needs to be held for 24-48 hours before an apheresis procedure?
ACE inhibitors
Can cause hypotension, bradycardia, and dyspnea
2000
Which substance can neutralize anti-P1?
Pigeon egg fluid, hydatid cyst fluid
2000
The rare X-linked Chronic Granulomatous Disease is associated with this unusual red cell phenotype?
The McCleod phenotype (Kell null with weak k, Kpb & Jsb)
2000
What is the cause of post-transfusion purpura (PTP)?
Anti-HPA antibodies; typically anti-HPA-1a
2000
Minimum concentration of fibrinogen in a cryo unit?
150 mg
2000
How are bacterial infections screened for in platelet units?
Culture unit and test in parallel while the unit is on the shelf
2000
A 1 blood volume exchange removes what percentage of the patient's original plasma or RBCs?
65% (60%-70% acceptable answer)
2000
The Rh-null phenotype is associated with what red cell shape (Poikilocytosis)?
Stomatocytes
