HDFN
Antigens and Antibodies
Transfusion Reactions
Component Therapy
ID Screening
Apheresis
Final Jeopardy
Harry Potter Bonus Round
Hard Harry Potter Bonus Round
400
How much fetal blood does a standard vial of RhIg protect against?
30 mL
400
Antibodies which demonstrate weak reactivity against many cells in an antibody panel and continue to react at high dilutions are called?
High Titer Low Avidity (HTLA)
Examples include: Chido/Rogers (Ch/Rg), Sda, Cartwright, John Milton Hagen (JMH)
400
If symptoms are mild and resolve with treatment, the transfusion may be restarted carefully in this type of TR?
Allergic Reaction
400
What is the standard hemoglobin threshold for transfuing an RBC?
7.0 g/dl
400
What is the most likely organism a patient will be exposed to in a transfusion?
Bacteira, skin flora
400
Which medication class needs to be held for 24-48 hours before an apheresis procedure?
ACE inhibitors
Can cause hypotension, bradycardia, and dyspnea
400
What is in the core of Harry's wand?
Phoenix feather
A feather from the same Phoenix is in Voldemort's wand
400
Who were Ron and Harry's dates to the Yule Ball?
Parvati and Padma Patil
800
What is the titer cutoff for risk of HDFN?
16
800
Red blood cells that are resistant to lysis by urea may be negative for these antigens.
Kidd antigens
800
Which transfusion reaction does leukoreduction decrease the incidence of?
Febrile non-hemolytic
800
What is the threshold for platelet transfusion to prevent spontaneous bleeding?
10 K
800
What disease is transmitted within WBC?
CMV
800
Name a indication for TPE where Plasma is required as the replacement fluid (instead of albumin)?
TTP
Patients with liver failure
800
What type of broom did Harry get in Book 3?
Firebolt
800
Who was the Care of Magical Creatures professor before Hagrid?
Professor Kettleburn
1200
Which antibody was a lower titer threshold than the standard?
Anti-K
1200
Which substance can neutralize anti-I?
Breast milk
1200
How can TACO be prevented?
Transfuse slowly, only when necessary
1200
Which patient population benefits from cold-stored platelets?
Bleeding patients
1200
If a RBC unit is contaminated with bacteria, what is the most likely specices?
Yersinia enterocolitica
1200
What anticoagulant is used during apheresis?
Citrate
1200
What form does the Boggart take for Professor Lupin?
Full Moon
1200
What is the name of the conductor of the Knight Bus?
Stan Shupnik
1600
What does the Kleihaur-Betke test detect?
Hemoglobin F
1600
If you lack the U antigen, what other major structure on your RBCs do you lack?
Glycophorin B
1600
TRALI is most commonly caused by what?
HLA antibodies in the donor unit
1600
How much is a single pool of cryo expected to increase a patients fibrinogen level?
50-100 mg/dL
1600
What is the deferral length for travel to a malaria endemic region?
3 months
1600
How is blood separated in apheresis procedures?
Density gradients with centrifugation
1600
What can Rita Skeeter turn into?
A beetle
1600
What Vault number was the Sorcerer's Stone kept in?
Vault 713
2000
What is the name of the qualitatve (screening) test for fetal-maternal hemorhage
Rosette Test
2000
What is the name for HLA antigens expressed on RBCS?
Bg antigens
Bg(a) - HLA B7; Bg(b) - HLAB17; Bg(c) - HLA-A28
2000
What TRALI mitgation strategy is used in the USA (and many other countries)?
Male only plasma
2000
Who is a candidate for granulocyte transfusion?
Patient who is non-responsive to antimicrobials with a fungal or bacterial infection and an ANC of <500
2000
What is the window period for HIV?
~ 9 days
2000
A 1 blood volume exchange removes what percentage of the patient's original plasma or RBCs?
65% (60%-70% acceptable answer)
2000
What 2 ethnic populations more commonly lack both Kidd antigens? Double Kidd-null
Polynesians and Finns
2000
How many points, for Gryffindor, did Neville earn at the end of book 1 for standing up to his friends?
10 points
2000
What are the employees of the Department of Mysteries called?
Unspeakables