Cancer Genetics
This is the process of transforming normal cells into malignant cells.
Carcinogenesis
True or False? When a cell sustains DNA damage, it is always cancerous.
False
This is the functional unit of life. They are organized into tissues --> organs --> organ systems.
Cell
This project lead to mapping and sequencing of the human genome.
Human Genome Project
At Winship, we use the following genomic vendors:
Caris, Guardant, Signatera, Invitae & Oncotype
These are identifiable risks that influences a patient's pre-disposition risk to cancer. Give me examples!
Non-Modifiable vs. Modifiable Risks
These cancers are caused by a combination of inherited and acquired mutations.
Hereditary cancers
This genetic material is found in all human cells and stores information for living organisms
DNA (deoxyribonucleic acid)
True or False? Previous Oncology Treatments can increase the risk of cancer.
True
This genomic vendor analyzes cell-free DNA and RNA from plasma, plus genomic DNA and messenger RNA from circulating white blood cells (WBCs) to distingush mutations
Caris Assure
This is the phenomonen of cancer cells moving to other areas of the body.
Metastasis
This type of cancer is caused by the build up of acquired mutations.
Sporadic cancers
This is where genetic data (DNA) is stored within the cell.
Nucleus
This kind of testing checks for one gene.
Single Gene Testing
This Guardant test has a 5 day turnaround time.
Guardant 360cdx
This terms refers to agents that can cause cancer. Give me examples!
Carcinogens
This mutation is associated with breast cancer and prostate cancer.
BRCA genes
This is a sequence of DNA which functions as the basic unit of heredity passed from parent to child.
Gene
This kind of testing tests for multiple genes.
Multi-Gene Panel Testing
This genomic vendor is used for breast cancer
Oncotype
This is the process of looking at cancer cells underneath a microscope to determine their malignancy.
Grading
This syndrome is associated with inherited colon cancer.
This molecule is a product from gene and functions to carry out the functions of the cells.
Protein
These are drugs used to precisely identify and attack specific molecules and genetic changes for a person's cancer.
Targeted Therapy
This genomic vendor tests for presence or absence of molecular residual disease over time.
Signatera