Transcription
Protein factor with kinase domain needed to push RNA poll II down the DNA template and start transcription.
What is TFIIH
Protein that binds to poly A tail to indicate that the mRNA is ready to leave the nucleus.
What is the poly A binding protein?
A low Km and high K value.
What is tight binding of the substrate/ little substrate needed for reaching maximum catalytic rate of reaction?
ATP binding to a site other than the active site on phosphofructokinase causing the active site to not bind substrate as well.
What is negative allosteric linkage?
Protein has many hydrophobic regions forming 'start' and 'stop' signals.
What is a multipass membrane protein?
Sequence needed to terminate transcription by signaling cleavage factors in eukaryotes.
What is AAUAAA?
Ribozyme for forming new peptide bond of growing polypeptide chain.
What is peptidyl transferase?
Misfolded proteins that contain parallel beta-pleated sheets and can spread to cause other proteins to misfold and cause disease.
What are prion proteins?
When enough pyruvate is made through glycolysis, pyruvate can act as an allosteric regulator to shut off the pathway.
What is feedback regulation?
Protein that binds to both the hydrophobic signal sequence and stalls translation by binding to the A site of the ribosome.
What is the SRP.
What are poly A binding proteins and nuclear transport receptor?
Anticodon of initiator tRNA.
What is 5' CAU 3' ?
Magnesium for polymerases to help form the charge needed to bind to nucleic acids.
What are cofactors?
What is the proteasome?
Sec 62 and Sec 63 are required along with Bip to 'pull' proteins into the ER lumen.
What is post-translation into the ER.
Very first transcription factor to bind to the promoter for formation of the transcription initiation complex in eukaryotes.
What is TFIID with the TBP?
Pathway name for mRNAs with exon junction proteins after the stop codon.
What is non-sense mediated decay?
What are domains?
Enzyme activity of TFIIH that adds phosphates to the C-terminal domain of RNA pol II.
What is a kinase?
Proteins like the small subunit of RUBISCO needed for photosynthesis but with the gene in the nucleus of the host plant cell need to pass through these translocators.
Added to the 5' end of the new transcript to prevent nucleases from destroying it as soon as transcription begins.
What is the guanine cap?
Protein that binds to incoming aminoacyl-tRNA and will not dissociate until the GTP is hydrolyzed to GDP which only happens if the 18s rRNA of small subunit binds strongly to codon and matching anticodon of the incoming tRNA.
What is EF1?
Regions that do not have distinct secondary structure and usually act as hinges.
What are IDR - intrinsically disordered regions?
Protein that binds to other proteins to help assemble them for catalytic activities.
What is a scaffolding protein?
Most proteins that function in the ER, Gogli, lysozome, cell membrane or exterior to the cell, and/ or require modification such as glycosylation, disulfide bridges, GPI anchor go through this process to get into the ER.
What is co-translation?