Antimalarials
What day do people start experiencing symptoms of malaria?
10 days after tissue invasion
What is the name of the anthelmintic drug we need to know for the test?
Ivermectin (this is an antiparisitic agent)
An international traveler diagnosed with malaria is admitted to the emergency department and is prescribed mefloquine hydrochloride. The nurse anticipates that which laboratory test will be ordered?
A. Liver function test (LFT)
B. blood glucose
C. sputum culture and sensitivity
D. white blood cell count
A. Liver function test (LFT)
What are malaria symptoms similar to?
Name the symptoms
They are flu like symptoms!
fever, chills, sweating, malaise, HA, vomiting, diarrhea
How should anthelmintic drugs be administered?
How long is this drug usually given?
Topically and orally, take on an empty stomach
Usually given 1-3 days
A patient with a history of malaria who is being treated with chloroquine is in the clinic for a follow-up visit. What should the nurse advise the patient to do?
A. get frequent hearing checks
B. take antimalarials before meals
C. get frequent testing of stool specimens
D. avoid sun exposure
D. avoid sun exposure
What are some ways to prevent malaria?
Bug sprays with DEET
Mosquito nets
Treat clothing
Tents
Permethrin (insect repellent
True or False: Ivermectin is absorbed better on an empty stomach
TRUE
A 50 year old woman is being discharged from the hospital after treatment for malaria. Which teaching topic would best inform the patient about adverse reactions?
A. the occurrence of headaches
B. experiencing dizziness
C. developing mild pruritus
D. skin and eyes that appear yellowish
D. skin and eyes that appear yellowish
Name the antimalarial drugs (there are 4)
the QUINE drugs:
Chloroquine
Quinine sulfate
Hydroxychloroquine
Mefloquine
What should you monitor while on anthelmintic drugs?
Ophthalmic exams (eye exams before, during, and after treatment)
Obtain and monitor stool examinations
Monitor hepatic enzymes
ALT, AST, and pregnancy test prior to administration
A 30 year old woman presents with a recurrence of Trichomonas vaginalis infection, and metronidazole is ordered. The patient's history reveals which of the following contraindications?
A. a recent pregnancy test is negative
B. she previously took metronidazole and had no side effects
C. she drinks a glass of wine before bedtime
D. she takes an oral contraceptive
C. she drinks a glass of wine before bedtime
What are the side effects/adverse reactions of antimalarial drugs?
GI upset !!!!
retinal damage, 8th cranial nerve damage, renal impairment, cardiovascular effects
Side effects of anthelmintic drugs
Ocular opacity, elevated hepatic enzymes !!!!
dizziness, drowsiness, HA, weakness, lymph node swelling, tachycardia, GI distress