400
At the site of the injury, signs and symptoms of an animal or insect bite or sting may include pain, localized heat, and a wheal, which appears as __________.
A) an uncomfortable depression in the skin
B) a series of small, raised pustules
C) a raised, well-defined area of the skin
D) a large area of red, blotchy skin
C) a raised, well-defined area of the skin