Brand and generic names
glucophage
What is metformin?
inhibits the enzyme DPP-4
what are DPP-4 inhibitors
glimepiride
what is a sulfonylureas?
absolute lack of insulin
Type 1
Januvia
What is Sitagliptin?
inhibits glucagon secretion and lowers preprandial rise of glucose levels
what are amylin agonist?
pioglitizone
What is a TZD?
common in older and overweight patients
type 2
gluctrol
what is glipizide?
acts as agonist of PPAR-gamma, lowers insulin resistance and increases glucose uptake by muscle cells
What are thiazolidinediones (TZDs)?
liraglutide
what is a GLP-1 analog?
common manifestations include: polyuria and polydipsia
type 2
trulicity
what is semaglutide?
enhances insulin secretion by pancreatic beta-cells
What are meglitinides?
canagliflozin
what is a SGLT-2 inhibitor ?
requires exogenous insulin
type 1
synjardy
what is empagliflizon and metformin
binds to ligand- specific receptor on cytoplasmic face of pancreatic-beta cells, mediating closure of ATP-sensitive K+ channel, causing depolarization, and calcium entry into the cell, thereby stimulating insulin release
What are sulfonylureas?
miglitol
What is a alpha-glucosidase?
Humalog can be used to treat...
Type 1 and type 2