Black Box Warnings
Oxycodone
Addiction, abuse, misuse
REMS
Respiratory Depression
Accidental Ingestion
Neonatal Withdrawl
Interactions with CYP3A4 inducers, inhibitors
Interactions with benzodiazepines or CNS depressants
Risk of medication errors with oral solution
Drowsiness
GC is a 99 y/o woman presenting to pick up a prescription for Kadian (morphine sulfate ER). She tells you that she has trouble swallowing, how would you counsel her?
Kadian capsules be opened and sprinkled over apple sauce for immediate administration
Rapid acting insulin
Haloperidol
Haldol
Acetaminophen
Lidocaine
hypersensitivity: contact dermatitis
systemic toxicity: topical administration to mucous membranes or use of nebulized lidocaine can cause extreme CNS excitation
methemoglobinemia
Your pain patient wants to know if she can use her heating pad over her fentanyl patch for additional pain relief
NO
Humulin R's Onset
30 minutes
Fluoxetine
Prozac
Hepatotoxicity
Pancreatitis
Fetal Risk
Acute Liver Failure in patients with mitochondrial disease
Lisdexamphetamine
cardio: tachycardia, arrhythmia, syncope, increased blood pressure
metabolic: growth suppression, weight loss
psychiatric: mania, aggression, hositlity, suicide ideation
serotonin syndrome
Take in the morning on an empty stomach 30-60 minutes before food.
BONUS: Do not take within 4 hours of calcium, iron, or a bile acid sequestrant.
Double Points: The two adverse reactions associated with insulin injectables
weight gain and injection site reactions
Donepezil
Aricept
Complex Sleep Behaviors
Baclofen
CNS Effects: confusion, dizziness, drowsiness, sedation, asthenia
Withdrawl effects: seizure, insomnia, agitation, muscle rigidity, fever, HTN
An opioid naive patient presents to pick up a Hycet script following orthopedic surgery. Counsel him.
Constipation: osmotic and stimulant medications for prophylaxis
S/S of opioid overdose
Narcan
Insulin Glargine's Peak
Eszopiclone
Lunesta
Levothyroxine
Donepezil
Cardio: bradycardia, AV block, prolonged QT interval, HTN, syncope
GI: N/V/D, weight loss, anorexia
A patient comes to your pharmacy with a new prescription for Zoloft. Their chart includes the following current meds: Metformin (diabetes), Duloxetine (pain), Lisinopril (HTN), HCTZ (HTN). Why will you not fill this Zoloft?
DDI: Risk of serotonin syndrome with two serotonergic agents. Sertraline (SSRI), Duloxetine (SNRI)
Room temperature stability of Tresiba
56 days
Lubiprostone
Amities