Upper GI
Lower GI
Liver
Pancreas & Gallbladder
Pharmacology
100
Achalasia is a failure of relaxation of the: a. Upper esophageal sphincter b. Middle esophageal sphincter c. Lower esophageal sphincter d. Pyloric sphincter
What is (c) LES.
100
This is a classic characteristic of ulcerative colitis: a. Skip lesions b. Noncaseating granulomas c. Migratory polyarthritis d. Bloody diarrhea
What is (d) bloody diarrhea.
100
Which is the most common cause of portal hypertension worldwide? A. Chronic hepatitis B infection B. Chronic hepatitis C infection C. Alcoholic liver disease D. Nonalcoholic fatty liver disease E. Schistosomiasis infestation
What is E) Schistosomiasis infestation
100
This mnemonic is often used to remember the causes of acute pancreatitis: a. GET SMASHED b. GET TRASHED c. GET WASTED d. BINGE DRINKING IS VERY BAD
What is (a) GET SMASHED.
100
This H2-antagonist blocks histamine receptors on parietal cells: a. Omeprazole b. Octreotide c. Cimetidine d. Misoprostol
What is (c) cimetidine.
200
Barrett's esophagus is an example of: a. Dysplasia b. Hyperplasia c. Neoplasia d. Metaplasia
What is (d) metaplasia.
200
This colorectal cancer is caused by a mutation in DNA mismatch repair genes: a. Familial Adenomatous Polyposis b. Gardner Syndrome c. Turcot Syndrome d. Hereditary Nonpolyposis Colorectal Cancer
What is (d) HNPCC / Lynch Syndrome.
200
The following is least likely associated with hepatocellular carcinoma? A. Primary biliary cirrhosis B. Chronic hepatitis C C. Chronic hepatitis B D. Wilson disease E. Hemochromatosis
What is D) Wilson disease
200
This is the medical term for gallbladder inflammation (typically secondary to obstruction): a. Cholecystitis b. Cholelithiasis c. Choledocholithiasis d. Cholangitis
What is (a) cholecystitis.
200
Infliximab (used for IBD) is a monoclonal antibody to this target: a. CD20 b. TGF-beta c. IL-6 d. TNF-alpha
What is (d) TNF-alpha.
300
Duodenal ulcer pain classically: a. Decreases with meals b. Increases with meals c. Waxes and wanes with the tide d. Decreases with cold fluids
What is (a) decreases with meals.
300
This congenital megacolon is characterized by lack of ganglion cells due to failure of neural crest cell migration: a. Zenker Diverticulum b. Angiodysplasia c. Hirschsprung Disease d. Meconium Ileus
What is (c) Hirschsprung Disease.
300
The most common cancer in liver in the US is: A. Hepatocellular carcinoma B. Cholangiocarcinoma C. Metastatic carcinoma D. None of the above
What is C) metastatic carcinoma
300
This autoimmune destruction of intralobular bile ducts causes pruritus, jaundice, dark urine, light stools, and hepatosplenomegaly: a. Primary sclerosing cholangitis b. Biliary atresia c. Primary biliary cirrhosis d. Secondary biliary cirrhosis
What is (c) Primary biliary cirrhosis.
300
This agent is used to treat acute variceal bleeds, acromegaly, VIPomas, and carcinoid tumors: a. Misoprostol b. Octreotide c. Dexamethasone d. Ondansetron
What is (b) octreotide.
400
A woman with Graves is anemic with high MCV despite taking iron daily. She has frequent abdominal pain. Likely Dx is: a. Chronic type A gastritis b. Chronic type B gastritis c. Acute gastritis d. Plummer-Vinson syndrome
What is (a) Chronic type A gastritis.
400
"False" diverticula (pseudodiverticula) involve outpouching of which layer(s): a. Lumen enlargement only b. Outpouching of mucosa only c. Outpouching of mucosa and submucosa d. Outpouching of mucosa, submucosa, and muscularis
What is (c) mucosa and submucosa.
400
The following about primary sclerosing cholangitis is true: A. ERCP is the gold standard for its diagnosis. B. It affects only the small and medium-sized bile ducts. C. It is typically associated with anti-mitochondrial antigens. D. It is more common in women. E. It is more commonly associated with Crohn’s disease than with ulcerative colitis.
What is A) ERCP is the gold standard for its diagnosis Endoscopic retrograde cholangiopancreatography (ERCP)
400
A patient is incidentally found to have a calcified gallbladder on abdominal X-ray. Recommended course of action is: a. No action needed b. Annual screening with CT or U/S c. Decrease fat intake d. Prophylactic cholecystectomy
What is (d) prophylactic cholecystectomy (porcelain gallbladder has high rates of GB carcinoma)
400
PPI's do NOT increase the risk of: a. Hypermagnesemia b. Pneumonia c. C. difficile infection d. Hip fractures
What is (a) hypermagnesemia (but they do increase risk of hypomagnesemia).
500
This painless, slow-growing mass is the most common malignant salivary gland tumor: a. Pleomorphic adenoma b. Warthin (papillary) tumor c. Mucoepidermoid carcinoma d. Wharton's (ductal) adenocarcinoma
What is (c) Mucoepidermoid carcinoma
500
This malabsorption syndrome presents in early childhood with failure to thrive, steatorrhea, acanthocytosis, ataxia, and night blindness: a. Tropical Sprue b. Whipple Disease c. Disaccharidase Deficiency d. Abetalipoproteinemia
What is (d) abetalipoproteinemia.
500
The typical histopathology of alcoholic liver disease includes the following EXCEPT: A. Steatosis B. Bile duct injury C. Ballooned hepatocytes D. Mallory-Denk bodies (Mallory hyalines) E. Centrilobular perivenular/pericellular fibrosis
What is B) bile duct injury
500
A 60 year-old African-American male with diabetes presents with weight loss, jaundice, and abdominal pain radiating to back. On exam, you note redness and tenderness on palpation of extremities. This constellation of signs and symptoms is known as: a. Dubin-Johnson Syndrome b. Deckers Syndrome c. Whipple Syndrome d. Trousseau Syndrome
What is (d) Trousseau Syndrome (migratory thrombophlebitis).
500
Reglan (metoclopramide) is contraindicated in patients with this: a. Hypotension b. Huntington's disease c. Parkinson's disease d. Stroke
What is (c) Parkinson's disease.
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