Spatial information is coded in this brain region.
What is the hippocampus?
100
This type of antidepressant drug has many dietary restrictions.
What are MAOIs?
100
What is the difference between a delusion and hallucination?
Delusion - beliefs that are contrary to reality
Hallucination - often auditory
100
This is often prescribed to bipolar patients and helps to stabilize mood.
What is Lithium?
100
What is Hebb's Rule?
"Neurons that fire together wire together" - a synapse increases in effectiveness bc of simultaneous activity of presynaptic and postsynaptic neuron - strengthens weak synapses.
200
Increased_______can be recorded from the hippocampus (dentate gyrus) after LTP.
What are EPSPs?
200
Antidepressants can normalize the volume of this brain region.
What is the hippocampus?
200
Name 3 negative symptoms of schizophrenia.
What is blunted affect (lack of emotional reactivity), impaired speech, social withdrawal, passivity, anhedonia, impaired attention, difficulty problem solving?
200
A GABA agonist is often prescribed to reduce the symptoms of this disorder.
What is Generalized Anxiety Disorder?
200
Antidepressants have been shown to increase levels of these 2 proteins in animal studies.
What is CREB and BDNF? (involved in hippocampus plasticity)
300
Someone who has difficulty remembering events that occur before brain damage suffers from:
What is retrograde amnesia?
300
Besides altered 5-HT metabolism, what is another hypothesis surrounding the development of this disorder.
What is ACh supersensitivity - receptors very responsive to ACh and produces greater effect.
300
Cocaine and other stimulants can produce the positive symptoms of schizophrenia because they....
Increase dopamine release in the brain.
300
What is the difference between unipolar and bipolar depression?
Bipolar - vary between depression and mania.
Unipolar - vary between depression and normal mood.
300
Patient H.M. suffered from loss of this type of memory.
What is declarative memory? (memories as facts and events)
400
What must happen before the NMDA receptor can be activated and its calcium channel opened?
Glutamate must bind and Mg++ removed from channel.
400
What are 2 criticisms of the Monoamine Hypothesis of depression?
Too simplistic.
No direct relationship.
Some drugs that boost monoamines are not AD.
Delayed therapeutic effect.
Measurement of amines inconsistent.
400
Atypical antipsychotics are different from other antipsychotic medication because they reduce these symptoms.
What are negative symptoms.
400
Altered 5-HT metabolism and lower levels of 5-HIAA has been found in some patients with this disorder.
What is borderline personality disorder?
400
What is the dexamethasone suppression test?
DEX is a synthetic cortisol - injected into patients - some depressed people are unable to suppress (lack of negative feedback and overactivity of HPA axis).
500
Why does Long Term Potentiation take a few does to form in the hippocampus?
The synapses must be strengthened.
500
Sexual dysfunction is an unusual side effect of this antidepressant and causes many people to discontinue use.
What are SSRIs?
500
Name 2 theories for the development of the negative symptoms of schizophrenia.