Who was Flossie Wong-Staal?
Education, Career, and Legacy of Flossie Wong-Staal
The HIV/AIDS Crisis
Challenges Faced Caused by HIV
Accomplishments of Flossie Wong-Staal
100

What was Flossie Wong-Staal's birth name? 

What is Yee Ching Wong?

100

Where did Flossie attend college at?

[Double points if you can list what she attended for]

What is the University of California, Los Angeles?

[2X Points: What are her undergraduate and graduate educations?]

100

What does HIV stand for?

What is Human Immunodeficiency Virus? 

100

What did the virus manage to do since doctors did not possess the tools to track it?

What is spread silently?

100

What did Flossie Wong-Staal do that became a huge scientific milestone?

What is clone the HIV virus?

200

In which country was Flossie Wong-Staal born in?
Double points if the city can be named!

What is Guangzhou, China?

200

What did Flossie obtain her Ph.D. in?

What is molecular biology?

200

When did medical professionals start noticing rare infections and cancers associated with weakened immune systems?

What is the early 1980s?

200

What kind of virus is HIV classified as?

[Triple Points if you can tell what this type of virus does!]

What is a retrovirus?

[3X Points: What is injecting its own genetic code straight into human host DNA?]

200

What "biological roadmap" did Flossie create to pinpoint genes tied to replication and infection?

What is HIV's genome?

300

Where did Flossie Wong-Staal's family flee to following the rise of the Chinese Communist Revolution?

What is Hong Kong?

300

Where did Flossie move to collaborate with experts on retroviruses?

What is the National Cancer Institute?

300

What were the three massive hurdles that scientists had to face during the 1980 outbreak?

What are no cure, no reliable treatment, and limited understanding of how it spread?

300

Why was the development of a cure hindered?

[Hint: Three factors]

What are lack of time, testing, and resources?

300

What vital procedure was allowed in medical centers after Flossie's groundbreaking insights?

What are blood transfusions?

400

Where did Flossie receive her English name?

What is a Catholic girls' school?

400

Later in her career, where did Flossie shift some of her research attention?

[Hint: A separate viral illness]

What is Hepatitis C?

400

What was HIV notoriously difficult for?

What is mutating rapidly?

400

[Double Points!]

What is the term for when a virus alters its physical structure so rapidly that current medications fail to fight it?

What is hypermutation?

400

What was created when Flossie's research laid the foundational evidence required to make this treatment?

[Hint: Drug resistance]

What are "drug cocktails"?


500

How did Flossie grow interested in science?

What is when she learned that women were underrepresented in scientific research?

500

When collaborating with other scientists, what did Flossie find out about the retrovirus?

[Hint: Genetic Code]

What is retroviruses store genetic information as RNA instead of DNA?

500

[Double Points!]


What cell(s) does HIV damage?


What are CD4/T-helper cells?

500

What long-term complication happened to the antiviral medicines, rendering them less effective?

What is the virus becoming resistant?

500

What was created more commercially when Flossie's meticulous mapping led directly to it?

What are HIV blood tests?

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