BIOMARKERS
A measurable biological molecule that signals a normal or abnormal process, disease, or condition in the body.
What is a Biomarker?
DNA mutations, gene copies, chromosomal rearrangements.
What is a Genetic Biomarker?
EGFR/ALK/ROS1/MET - Genetic mutation found in non-small cell ___ cancer?
What is Lung cancer?
Proteins, RNA, epigenetic changes, metabolites.
What is a Molecular Biomarker?
This is the use of biomarkers to detect cancer before symptoms appear.
Chromosomal Rearrangements are gene fusions that create new cancer-driving proteins (ex. BCR-ABL (CML))
What is a Genetic Biomarker?