Enzymes
This enzyme removes glucose molecules from glycogen by breaking α-1,4 glycosidic bonds.
What is glycogen phosphorylase?
This hormone stimulates glycogen breakdown during fasting.
What is glucagon?
The major product released from glycogen.
What is glucose-1-phosphate?
This inherited disease results from a deficiency of muscle glycogen phosphorylase.
What is McArdle disease?
Glycogen is primarily stored in these two organs.
What are the liver and skeletal muscle?
This enzyme transfers three glucose residues during glycogen breakdown.
What is the debranching enzyme?
This hormone inhibits glycogen breakdown after eating.
What is insulin?
The molecule produced after phosphoglucomutase acts.
What is glucose-6-phosphate?
This disease results from deficiency of glucose-6-phosphatase.
What is Von Gierke disease?
True or False: Muscle cells contain glucose-6-phosphatase.
False
This activity of the debranching enzyme removes the remaining α-1,6 linked glucose.
What is α-1,6-glucosidase?
This hormone rapidly stimulates glycogenolysis during exercise or stress.
What is epinephrine?
Approximately this percentage of glycogen breakdown produces glucose-1-phosphate.
What is 90%?
Patients with McArdle disease commonly experience this symptom during exercise.
What are muscle cramps or exercise intolerance?
This second messenger is produced after glucagon binds its receptor.
What is cAMP?
This enzyme converts glucose-1-phosphate into glucose-6-phosphate.
What is phosphoglucomutase?
This molecule allosterically activates glycogen phosphorylase in muscle.
What is AMP?
This type of bond is broken by glycogen phosphorylase.
What is an α-1,4 glycosidic bond?
During fasting, glycogenolysis helps prevent this condition.
What is hypoglycemia?
Protein kinase A activates this enzyme before glycogen phosphorylase becomes active.
What is phosphorylase kinase?
This liver enzyme converts glucose-6-phosphate into free glucose.
What is glucose-6-phosphatase?
This enzyme activates glycogen phosphorylase by phosphorylation.
What is phosphorylase kinase?
This bond is cleaved by α-1,6-glucosidase.
What is an α-1,6 glycosidic bond?
This organ is primarily responsible for maintaining blood glucose through glycogenolysis.
What is the liver?
Put these in the correct order:
- Glycogen phosphorylase
- Phosphoglucomutase
- Glucose-6-phosphatase
1. Glycogen phosphorylase
2. Phosphoglucomutase
3. Glucose-6-phosphatase