Platelets, Petechias, and Purpuras
Flip it & Reverse it
Smears & Tears
Trauma Drama
Complete the Lyrics: 90's edition
100
First line therapies for this acute thrombocytopenic condition include steroids and IVIG.
ITP
May also use Rhogam in Rh + individuals...
100
A patient with a mechanical heart valve on a vitamin K antagonist presents with a massive intracerebral hemorrhage; to rapidly reverse their coagulopathy, you administer Vitamin K and this specific product containing factors II, VII, IX, and X.
Four Factor Prothrombin Complex Concentrate
KCENTRA, BALFAXAR
weight based and fixed-dose regimens
100
The presence of these fragmented red blood cells on a peripheral smear is the hallmark of microangiopathic hemolytic anemia.
Schistocytes (or helmet cells)
100
In a massive transfusion protocol for trauma, you typically aim to resuscitate the patient using this specific ratio of Packed RBCs to FFP to Platelets.
1:1:1
100
When I was young I knew everything
And she a punk who rarely ever took advice
Now I'm guilt stricken, sobbing with my head on the floor...
Stop a baby's breath and a shoe full of rice
The Verve Pipe: Freshman
200
You may reach for this med instead of heparin, in a patient with a history of HIT.
*Argatroban* - direct thrombin inhibitor.
Will also take Bivalrudin / Fondaparinux
200
Derived from salmon sperm, this classic anticoagulant reversal agent acts by binding directly to unfractionated heparin, but carries a risk of anaphylaxis, especially in patients with prior NPH insulin exposure.
Protamine sulfate
200
In a patient with G6PD deficiency, oxidative stress leads to the formation of these denatured hemoglobin inclusions within the red blood cells.
Heinz bodies
200
When administering Tranexamic Acid (TXA) in trauma, the CRASH-2 trial demonstrated that the mortality benefit is lost if it is given beyond this specific time window from the injury.
3 hours
200
I’m never alone
I’m alone all the time
are you at one
or do you lie
we live in a wheel
where everyone steals but when we rise it’s like...
Strawberry Fields
BUSH - Glycerine
300
Your patient with acute anemia, thrombocytopenia, and ischemic CVA likely has THIS disease.
Also, what is the initial treatment?
TTP
Plasmapheresis / Plasma Exchange.
300
This specific monoclonal antibody is the FDA-approved reversal agent for the direct thrombin inhibitor dabigatran.
Idarucizumab (Praxbind)
300
Following the removal of the spleen, as in trauma or autosplenectomy from sickle cell disease, you expect to see these nuclear remnants on a peripheral blood smear.
Howell-Jolly bodies
300
This trial revealed that TXA use in the setting of TBI may reduce the risk of head injury associated deaths by several percentage points.
CRASH-3
300
It won't stop, I won't come down, I keep stock
With a tick-tock rhythm, a bump for the drop
And then I bumped up, I took the hit that I was given
Then I bumped again, then I bumped again, I said...
Third Eye Blind - Semi-Charmed Life
400
You'd be remiss to not think of this disease in a child with HTN, dark urine, and renal failure after eating tainted red meat.
HUS
E. coli O157:H7
400
This is the preferred dose and route of Vitamin K when utilized for INR > 10 without major bleeding.
2.5-5mg PO
Reduced rates of anaphylaxis
INR will dec over 24-48 hours via oral route administration
400
This classic finding on a peripheral smear, resembling stacks of coins, is seen in hyperviscosity states like multiple myeloma.
Rouleaux formation
400
In a massive transfusion protocol for hemorrhagic shock, you must closely monitor for this specific electrolyte abnormality caused by the metabolism of citrate.
Hypocalcemia
- For each MTP round (6 PRBC), give 1-2 grams of CaCl2 or 3-6 grams of calcium gluconate.
- (Calcium gluconate is preferred if given via a peripheral line.)
- Follow iCa if possible, target normal to mildly elevated iCa
400
Tell Sanchito that if
He knows what is good for him
He best go run and hide
Daddy's got a new Forty-Five
Sublime - Santeria
500
This specific protease enzyme deficiency can lead to uncleaved ultra-large von Willebrand factor multimers.
ADAMTS13
500
AstraZeneca has voluntarily withdrawn this medication from the U.S. market, effective December 22, 2025, due to safety concerns regarding increased risks of blood clots (thrombosis) and death.
Used for reversing apixaban and rivaroxaban in emergencies.
Andexxa (andexanet alfa)
500
A patient with DIC or a severe hemolytic state will often have a significantly decreased level of this specific protein, which binds free hemoglobin in the blood.
Haptoglobin
500
Given the case of traumatic brain bleeding in the setting of aspirin use with normal platelet level, this is the recommended indication for platelet transfusion.
Prior to Emergency Craniotomy or ICP monitor placement
Outside of these indications, may inc. rate of morbidity/mortality (PATCH trial 2016)
500
How can I help it if I think you're funny when you're mad?
Trying hard not to smile though I feel bad
I'm the kind of guy who laughs at a funeral
Can't understand what I mean?
Well, you soon will
I have a tendency to wear my mind on my sleeve...
I have a history of taking off my shirt , its been...
One Week by the Barenaked Ladies.