Peto's Paradox
What is Peto's Paradox
Peto’s paradox is the paradox involving fatal cancer risk vs size of animal. One would assume that the larger the size, the larger the more cancer the animal would get. Yet, somehow, that’s not the case. Instead the larger the animal the less risk of a case of fatal cancer.
What percent of cancer related deaths are related to drug resistance?
What is 90%
What are hyper tumors?
Hyper tumors can be explained pretty simply: they are the tumors of the tumor. They form when a cancer becomes extra competitive and essentially leeches off itself.
What animal is most commonly used as an example of Peto's paradox?
What is WHALES
Why are hyper tumors an theoretical solution to drug-resistant cancers?
The cancer targeted cannot build up a resistance to anti-cancer drugs because none are being used. Making the treatment more sustainable and reliable
What is Tumorigenicity?
The ability of the cancer cells to form more tumors.
Why is cancer less deadly in whales?
Tumors in whales take a while to grow to a dangerous size. In that time hyper tumors come in and keep the tumor from becoming dangerous by constricting its size of killing it off entirely.
Have hyper tumors been tested in living organisms in order to create a treatment option?
What is NO
Have the ability to form any type of cancerous cell through cell differentiation.
How long can whales live?
What is 200 years
How can the addition of anti-cancer drugs affect the treatment of hyper tumors?
They can slow and even kill the hyper tumors rendering the treatment useless
What is Angiogenesis?
The formation of new blood vessels from existing ones
How much do whales weigh
Up to two hundred tons
What source is this hyper tumor as a treatment from?
Evolution, Medicine, and Public Health, Volume 11, Issue 1
What is CRISPR?
A gene editing software