ADRs/Drug Interactions
This medication causes dose-dependent neuro- and nephrotoxicity
What is cyclosporine
Your immune system is separated into these two main categories
What are innate and adaptive
Prograf
What is tacrolimus
This medication requires levels to be monitored
What is Prograf
Transplant patients should avoid these two fruits
What are grapefruit and pomegranate
This type of cell is responsible for producing antibodies
What are B lymphocytes
Thymoglobulin
What is rabbit antithymocyte globulin (rATG)
These two labs should be monitored if patients are on any kind of immunosuppressive therapy
CBC and CMP
This commonly used maintenance drug can cause hyperkalemia, hypertension, and hyperglycemia
What is Prograf
This type of cell is responsible for cell-mediated immunity
What are T lymphocytes
Neoral/Sandimmune
What is cyclosporine
Sirolimus requires this type of level to be drawn to adjust dosing
What is a trough
This medication can cause impaired wound healing and mouth sores
What is sirolimus
This type of cell is responsible for presenting a foreign substance to T-lymphocytes
What are antigen presenting cells (APCs)
Campath
What is alemtuzumab
Thymoglobluin should not be given if platelet count and WBC are below these levels
What is a platelet count < 50,000 and WBC < 2,000
Allopurinol and febuxostat can increase the risk of accumulation and toxicity of this drug
What is azathioprine
This is the name for the "signal 2" in the three-signal model of alloimmune response; it involves CD80 and CD86 binding to CD28
What is costimulation
Myfortic
What is mycophenolate sodium
This medication is contraindicated in patients who are EBV seronegative or have an unknown EBV status
What is Belatacept