Nutritional Anemia
Most common nutritional cause of anemia in children and adolescents.
What is iron deficiency?
This condition is caused by passage of maternal antibodies against fetal RBC antigens.
What is isoimmune hemolytic disease of the newborn?
These two laboratory values are necessary to help guide diagnosis of cause of anemia.
What are MCV and Reticulocyte counts?
Hydroxyurea reduces pain crises and acute chest syndrome by increasing this.
What is fetal hemoglobin (Hb F)?
The two antibiotics of choice for a patient admitted with acute chest syndrome.
What are ceftriaxone and azithromycin?
An infant that only drinks goat's milk will likely be deficiency in this vitamin/mineral?
This antibody is the cause of warm autoimmune hemolytic anemia.
What is IgG?
The likely cause of a hemoglobin of 9.5g/dL in a term 8 wo infant
What is physiologic nadir?
This prophylactic medication dramatically reduced infection related mortality in SCD.
What is penicillin prophylaxis?
The likely etiology of an 8 yr old SCT pt with colicky RUQ pain, hyperbilirubinemia, and vomiting.
What is cholelithiasis?
This vitamin must be checked prior to initiating folic acid for folic acid deficiency to prevent worsening neurologic symptoms.
What is vitamin B12?
This test looks for red blood cell coated antibodies by adding a anti-IgG reagent.
What is the Direct Coomb's Test?
This test is often used to test for hemolysis but of limited utility in newborns.
What is haptoglobin?
This screening tool should start at age 2 to evaluate stroke risk.
What is transcranial doppler?
The acute management for ischemic stroke in SCD.
What is RBC exchange transfusion?
Intestinal location of vitamin B12 absorption.
What is the terminal ileum?
Infections associated with cold autoimmune hemolytic anemia.
What is Mycoplasma and EBV?
The most likely cause of a healthy well appearing 3 yo M with a hgb of 8 and decreased reticulocyte count
What is transient erythroblastopenia of childhood (TEC)?
Structural change in hemoglobin leading to sickle-shaped RBCs.
What is hemoglobin polymerization?
This IV medication to treat SCD inhibits adhesion of blood cells to P-selectin on endothelial cells.
What is crizanlizumab (Adakveo)?
This formula may help distinguish between iron deficiency anemia and thalassemia.
What is Mentzer Index (=MCV/RBC)?
Diagnostic laboratory result associated with hereditary spherocytosis.
What is increased osmotic fragility?
This value determines if the response to anemia is hypo-proliferative or hyper-proliferative.
What is reticulocyte production index?
Newborn screen result suggestive of sickle cell trait.
What is FAS?
The most likely infectious etiology of a pt with SCD, Hgb 4, retic 0.3%, plt 350K.
What is parvovirus B19?