Cholesterol-containing acids found in the bile that act like detergents to break up fats in the small intestine.
What is Bile acid Page 777 pharm
100
Name the Three Unmodifiable Risk Factors.
What is Genetic predispostions, Age, and Gender
100
This is the only Cholesterol Absorption Inhibitor.
What is Ezetimibe page 793
100
A fixed combination of extended-release niacin and lovastatin makes this drug.
What is Advicor page 789
100
This is the number one killer of adults in the United States.
What is CAD page 795
200
Carrier for lipids in the bloodstream, consisting of proteins, lipids, cholesterol, and so forth.
What is Chylomicron page 777 pharm
200
Name four Modifiable Risk Factors.
What is Gout, Cigarette smoking, Sedentary lifestyle, High stress levels, Hypertension, Obesity, Diabetes, bacterial infections, high-fat diet, menopause page 778
200
This lipid-lowering drugs category is the only category with children doses.
What is HMG-CoA Reductase Inhibitors (atorvastatin, lovastatin, pravastatin, and simvastatin)
page 786 and 784
200
Simvastatin and niacin makes what drug.
What is Simcor page 798
200
This is known as niacin or nicotinic acid.
What is Vitamin B page 795
300
Necessary component of human cells that is produced and processed in the liver, then stored in the bile until stimulus causes the gallbladder to contract and send the bile into the duodenum via the common bile duct; a fat that is essential for the formation of steroid hormones and cell membranes; it is produced in cells and taken in by dietary sources.
What is Cholesterol page 777 pharm
300
CAD is characterized by the progressive growth of what in the coronary arteries.
What is Atheromatous plaques or atheromas. Page 778
300
These are the first drugs of choice in the treatment of hypercholesterolemia in patients who are at risk for, or who have already developed, coronary artery disease.
What is HMG-CoA Reductase Inhibitors page 784
300
Combination of ezetimibe and simvastatin makes what drug.
What is Vytorin page 789
300
______ ______ alters the metabolism of the drugs, leading to an increased serum level of drug and increased risk for adverse effects, such as the potentially fatal rhabdomyolysis with renal failure.
What is Grapefruit juice page 790
400
Loosely packed chylomicron-containing fats, able to absorb fats and fat remnants in the periphery; thought to have a protective effect, decreasing the development of coronary artery disease.
What is High-density lipoprotein (HDL) page 777
400
Injury of the blood vessel also causes ________ and a ____________ of the vessel wall.
What is Scarring, Thickening page 778
400
Women of childbearing age should not take _______ _________ _______ but instead _________ ______ _________ if a lipid-lowering agent is needed.
What is HMG-CoA Reductase Inhibitors, Bile acid sequestrant page 784
400
5 or 10 mg amlodipine and 10,20,40, or 80 mg Atorvastatin makes this drug.
What is Caduet page 789
400
These lipid-lowering Agents stimulate the breakdown of lipoproteins from the tissues and their removal from the plasma.
What is Fibrates page 794
500
Tightly packed fats that are thought to contribute to the development of coronary artery disease when remnants left over from the LDL are processed in the arterial lining.
What is Low-Density lipoprotein (LDL) page 777
500
The _____, more ____-_____ atheromas appear to be more likely to rupture than the _______, _______ _________.
What is Softer, liquid-filled, stable, harder cores
page 778
500
A Combination therapy with a ______ ___ _______, a fibrate, or niacin may be necessary if lipid levels still can not be reduced.
What is Bile acid sequestrant page 784
500
Administer other oral medications 1 hour before or _ to _ hours after the bile sequestrant to avoid drug—drug interactions.
What is 4 to 6 page 788
500
Rimonabant is an endocannabinoic blocker that has been used in Europe as an _______ ______ ____.