Identify the condition of the liver

What is cirrhosis?
*Lumpy, bumpy nodules and is smaller. The nodules can be macrovesicular or microvesicular
Identify these cells/structures
What are hepatocytes/hepatic cords?
*Hepatic cords are the units that connect to other cords to make a hepatic lobule. Notice the prominent nucleoli in the center
Identify the yellow region

What is the hepatic/classical lobule?
*Central vein in the center of classical lobule, portal triad in the center of portal lobule
Ran an ultramarathon
Who is Calvin?
Part of their bucket list is trying Philly coffee shops
Who is Vy?
*Would recommend TwoPersons, a smaller branch opened up on 10th and Market
Identify the forest green small tubular structure
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What is the cystic duct (and spiral valves of Heister)?
*Where bile can go in and out of the gallbladder
Identify the thick vessel to the left of the big one on the right
What is the portal triad bile duct?
*The big vessel on the right is the portal vein and the small vessel beneath the duct is the hepatic artery
Identify the stage of this liver

What is stage 4/cirrhosis?
*Extensive fibrosis to portal triad and central vein is stage 4 fibrosis, while inflammation nearby (hard to spot) suggests grade 4
Brought blueberry muffins!
Who is Charlotte?
*If you baked them yourself we'll give you +50 points
Avid Celsius enjoyer
Who is Matt?
*Matt if you have a Celsius on hand I'll give you +50 points
Identify the vessel outlined in blue

What is the hepatic portal vein?
*Brings deoxygenated blood into liver, the hepatic proper artery and bile duct are adjacent
Identify the affected zone of this given steatosis

What is zone 3/centrilobular?
*Hard to see but macrovesicular (large droplets of fat) around the humongous central vein in the middle
Identify the thickened straight lines on this structure

What is the muscularis externa?
*There is NO submucosa NOR muscularis mucosa in the gallbladder!
For one of their truths, their last name means watermelon in another language
Who is Ali?
*Karpousis is Greek for watermelon
Death row meal included Eid Corned beef sandwiches and Soondubu jjigae
Who is Fathia?
Identify the anatomical lobe next to the gallbladder
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What is the quadrate lobe?
*Quadrate looks more quadrilateral and be closer to the anterior of human gifts
Identify the space the small vertical arrows are pointing to

What are the fenestrated endothelium?
*The liver endothelium is simple squamous to allow exchange of nutrients and waste
Identify the "open" region in the middle
What is Rokitansky-Aschoff sinus?
*Note the diverticula of the gallbladder mucosa with epithelium beneath the luminal surface
If they had to pick a different career in medicine, they would OWN a bakery or bar
Who is Grace?
Their hot take is liking S2 and S3 ripe bananas

Who is Ashley?
*Ashley if you baked your own banana bread you get +50 points
Identify the hole at the top
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What is the major duodenal papilla (ampulla of Vater OK)?
*The protrusion into descending duodenum is the papilla, while the ampulla is a small pouch right before this papilla that holds bile until sphincter of Oddi contracts
Identify the wispy gallbladder layer touching the liver

What is the adventitia?
*It is serosa ONLY if it is NOT near/touching the liver
Identify the process that leads to the center structures

What is ductular reaction?
*Canal of Hering stem cells will produce cholangiocyte bile ducts as chronic inflammation, seen with CK7/CK19+ IHC or lots of small ducts on histology
Been just under 3 weeks since their birthday
Who is Emma?
*Happy VERY belated birthday
Some of their favorite memories they showed were in summer camp including the giant water trampoline
Who is Noah?