Pharm. Vocab
The time required for the amount of a drug to be decreased by 50%
What is the half-life?
Many drugs produce their effects by doing this on the external surface of the cell membrane. Doing so does NOT give the cell new functions.
What is bind to receptors?
The division of the autonomic nervous system that is associated with the "rest/digest" response.
What is parasympathetic?
Food that must be avoided while a patient is taking statins.
What is grapefruit?
The antidote to warfarin overdose that can be found in dietary sources.
What is vitamin K?
The physiologic measurement used to determine pediatric medication dosing.
What is body surface area?
This drug administration method exerts its effects rapidly and allows drugs to be absorbed by the lungs.
What is inhalation?
The division of the autonomic nervous system that is associated with the "fight-or-flight" response.
What is sympathetic?
The suffix used for alpha1 blocking drugs.
What is -zosin?
Antidote to heparin overdose.
What is protamine sulfate?
The preferred drug name to use.
What is generic?
The organ associated with drug metabolism
What is the liver?
Alpha 1 blockade exerts their impacts on this body system.
What is the vascular system?
What is rhabdomyolysis?
Lab value monitored during heparin therapy.
What is aPTT/Anti-Xa?
The rapid hepatic inactivation of certain oral drugs.
What is the first pass effect?
The four phases of pharmacokinetics.
What are absorption, distribution, metabolism, and excretion?
An adrenergic agonist would have this effect on the heart.
What is tachycardia (increased HR)?
Antihypertensive medication class with -lol suffix.
What are beta-blockers?
Lab value monitored with warfarin therapy.
What is PT/INR?
A patient taking multiple medications needs to be aware of this which may cause intensified effects, diminished effects, or an entirely new effect.
What is drug-drug interactions?
This category of medication binds reversibly to receptors to reduce the functioning of the intended cells.
What are competitive antagonists?
A cholinergic (muscarinic) agonist would have this effect on the heart.
What is bradycardia (decreased heart rate)?
Primary hypertension will be treated with medication for this length of time.
What is lifelong?
Injectable anticoagulant that doesn't require frequent monitoring.
What are LMWH (enoxaparin)?
The objective of drug dosing is to maintain plasma drug levels within this.
What is the therapeutic range?
Name the three characteristics of an ideal drug.
What are efficacy, safety, and selectivity?
Anticholinergic side effects interfere with this branch of the autonomic nervous system.
What is parasympathetic nervous system? (Dry mouth, constipation, urinary retention)
Beta-blockers may cause this change to one of patient's vital signs and should be evaluated prior to administration.
What is bradycardia (decreased HR)?
The RN should be hyperaware of this effect of thrombolytics
What is increased risk of bleeding?
Name 3 points of education/assessments/precautions to take with a patient who is at risk of bleeding
Assess for prior intracranial hemorrhage, peptic ulcers and recent surgeries
Implement fall precautions
Minimize invasive procedures and physical manipulation of the pt
Closely monitor and assess for bleeding
Minimize concurrent use of anticoagulants