Night of the Living Vent
This sedative is recommended for sedation in mechanically ventilated adult patients admitted to the ICU when light sedation and/or a reduction in delirium is of highest priority.
(give generic name for points)
What is dexmedetomidine?
Dexmedetomidine is associated with a lower risk for delirium compared to propofol, particularly in older adults. When light, short-term sedation and reduction in delirium are of highest priority, dexmedetomidine is recommended over propofol.
Following a patient's first unprovoked seizure, these two diagnostic studies are recommended to evaluate the risk of seizure recurrence.
(Must answer both studies)
What are brain MRI and electroencephalography (EEG)?
In patients with a first seizure, the recurrence risk must be determined to establish the likelihood that the patient has epilepsy and whether antiseizure medications (ASMs) are warranted.
To make this determination, neuroimaging and electroencephalography (EEG) are indicated. MRI with contrast is the preferred neuroimaging test, as it is more sensitive than CT for finding abnormalities that suggest epilepsy.
These three classes of medications are considered first-line treatments for acute gout flares, with the choice of therapy guided by patient comorbidities, potential drug interactions, and preferences.
(can list off any of the three and points will be given)
What are colchicine, NSAIDs, and glucocorticoids?
In patients with early-stage cutaneous T-cell lymphoma (CTCL) confined to the skin, What is an appropriate first-line treatment?
(can accept any of the 3 modalities)
What are topical glucocorticoids, topical retinoids and/or ultraviolet (UV) phototherapy?
These three antibiotics are preferred treatment options for acute uncomplicated cystitis, with recommended treatment durations of 5 days, 3 days, and a single dose, respectively.
Can name any one for points
What are nitrofurantoin (5 days), trimethoprim-sulfamethoxazole (3 days), and fosfomycin (single dose)?
In patients with COPD requiring mechanical ventilation, this noninvasive respiratory support strategy can facilitate early extubation and reduce the duration of invasive mechanical ventilation.
What is BiPap?
Noninvasive positive-pressure ventilation with bilevel positive airway pressure is useful in facilitating early extubation of patients with COPD.
In patients presenting with convulsive status epilepticus, this class of medications is recommended as first-line treatment to rapidly terminate seizure activity.
What are intravenous benzodiazepines (or intramuscular midazolam)?
This syndrome is a rare complication of long-standing rheumatoid arthritis characterized by the classic triad of rheumatoid arthritis, neutropenia, and splenomegaly, with an increased risk of serious bacterial infections.
What is Felty syndrome?
Ductal carcinoma in situ (DCIS) is a noninvasive breast malignancy that can progress to invasive cancer. These two surgical treatment options are used to eradicate DCIS and reduce the risk of local recurrence.
(must give both answers)
What are lumpectomy (often followed by radiation therapy) and mastectomy?
Local treatment for ductal carcinoma in situ (DCIS) involves either mastectomy or lumpectomy, sometimes followed by radiation therapy; postlumpectomy radiation therapy improves disease-free survival but not breast cancer–specific mortality and can be omitted in some cases, especially in patients with small, low-risk breast cancer.
In patients with suspected community-acquired bacterial meningitis, this adjunctive anti-inflammatory medication should be administered before or with the first dose of empiric intravenous antibiotics to reduce neurologic complications, particularly in pneumococcal meningitis.
(Must state specific name)
What is dexamethasone?
In patients with acute coronary syndrome, oxygen therapy should not be initiated when oxygen saturation is at or above this percentage.
(Must give Exact number)
What is 90%?
Oxygen therapy should not be started in patients with acute coronary syndrome and an oxygen saturation of 90% or higher.
According to the American Heart Association 2025 guidelines, patients with acute intracerebral hemorrhage (ICH) presenting with a systolic blood pressure of 150–220 mm Hg should have their blood pressure maintained within this target systolic range to improve functional outcomes.
(Must give exact range)
What is 130 to <140 mm Hg?
In patients with rheumatoid arthritis who cannot tolerate methotrexate and have moderate disease activity, this conventional disease-modifying antirheumatic drug (DMARD) is the preferred alternative when no contraindications are present.
(must say exact name)
What is leflunomide?
In patients with resected stage IB–III non–small cell lung cancer without EGFR or ALK mutations, adding this class of medications after platinum-based chemotherapy can improve disease-free survival.
What are immune checkpoint inhibitors (immunotherapy)?
i.e pembrolizumab
In patients with acute uncomplicated pyelonephritis who are clinically stable and can be managed as outpatients, this class of oral antibiotics is a recommended empiric treatment option when local resistance rates are sufficiently low.
What are fluoroquinolones (ciprofloxacin or levofloxacin)?
In patients with ARDS, lung-protective mechanical ventilation reduces mortality by approximately 11% when using these recommended tidal volume and plateau pressure targets.
(Must give exact ranges/numbers)
What is tidal volume of 4 to 8 mL/kg of predicted body weight and a plateau pressure of less than 30 cm H2O?
In patients with convulsive status epilepticus who continue to seize despite appropriate first-line benzodiazepine therapy, these four antiseizure medications can be used as second-line treatment.
(Can list off only one and points will be rewarded)
What are fosphenytoin, valproate, levetiracetam, and lacosamide?
In patients with rheumatoid arthritis who fail to achieve low disease activity or remission despite optimally dosed methotrexate, adding one of these two classes of disease-modifying antirheumatic drugs (DMARDs) is the recommended next step.
(can say either one, points will be given)
What are biologic DMARDs or targeted synthetic DMARDs?
In patients with advanced-stage ovarian cancer, these three additional treatment strategies may improve outcomes when incorporated into standard chemotherapy or subsequent maintenance treatment.
(can list only one and points will be given)
What are intraperitoneal chemotherapy, bevacizumab (a VEGF inhibitor), and PARP inhibitors?
In patients with Staphylococcus aureus osteomyelitis involving retained orthopedic hardware that cannot be removed, this antibiotic is often added to another antistaphylococcal agent because of its activity against staphylococcal biofilms.
What is rifampin?
According to the 2026 Surviving Sepsis guidelines, critically ill patients with sepsis should receive glucose-lowering therapy when serum glucose persistently reaches ≥180 mg/dL, with this recommended target blood glucose range.
(Must give exact range)
What is 144–180 mg/dL?
The 2026 Surviving Sepsis guidelines recommend initiating glucose-lowering therapy in patients with persistent serum glucose levels of 180 mg/dL (10.0 mmol/L) or higher and targeting a glucose range of 144 to 180 mg/dL (8-10 mmol/L) in critically ill patients.
In a 20 year old female with major depressive disorder, what is the recommended medication, in the setting of two unprovoked seizures or one unprovoked seizure with significant electroencephalogram or MRI abnormalities?
(Must be the exact name)
What is Lamotrigine?
Lamotrigine is an excellent option for treating generalized epilepsy because it is safe to use in patients of childbearing potential and has mood-stabilizing properties, which may be helpful in this patient with an underlying mood disorder.
Before initiating allopurinol in patients of Asian, or African descent, genetic testing for this allele is recommended due to its strong association with life-threatening allopurinol hypersensitivity reactions.
(Must say entire allele)
What is HLA-B*58:01?
According to USPSTF recommendations, annual low-dose CT screening for lung cancer is indicated in eligible adults within this age range who have at least this many pack-years of smoking history. Screening should be discontinued after these many years of smoking cessation.
(will get points only with all 3 correct values/ranges listed)
What are 50–80 years of age, ≥20 pack-years, and 15 years since quitting smoking?
In patients with suspected health care–associated meningitis or ventriculitis, empiric treatment includes intravenous vancomycin plus one of these three antibiotics to provide broad-spectrum coverage against a specific organism.
(naming either of the three can give the points)
What are cefepime, ceftazidime, and meropenem?
(To cover Pseudomonas)