Diagnostics
What is the preferred diagnostic tool for Spinal Cord Compression?
What is MRI?
What Oncologic Emergency is related with back pain that is worse in the supine position?
What is Spinal Cord Compression?
Which labs are needed to calculate a Corrected Calcium?
What is Serum Calcium & Albumin?
What is first line treatment for ICANS?
What is one risk factor for developing Superior Vena Cava Syndrome?
Infection, Thrombosis, or invasion or compression of SVC
In addition to labs, what is one other diagnostic tool would you anticipate for Hypercalcemia of Malignancy?
What is ECG?
What Oncologic Emergency is related with upper extremity swelling, dyspnea, and dysphagia?
What is Superior Vena Cava Syndrome?
Is serum sodium high or low for a patient experiencing SIADH?
BONUS (100 pts): Is serum osmolality high or low?
What is the primary treatment for acute hypercalcemia of malignancy?
hydration with normal saline
What Oncologic Emergency occurs most frequently with AML?
What is Leukostasis?
What would you anticipate being ordered as part of a febrile neutropenia workup?
Blood Cultures, Chest X-Ray, Urine Culture, Sputum Culture (if resp symptoms present)
What Oncologic Emergency is related with arrhythmias, renal failure, paresthesia, and seizures?
What is Tumor Lysis Syndrome?
What is the definition of Hyperleukocytosis?
What is WBC>50-100K?
What medications are used to manage hyperuricemia?
What is Allopurinol and Rasburicase?
What is SIADH?
What are two tools used to diagnose SVC Syndrome?
What is CT Scan with Contrast and Chest X-Ray?
What are three symptoms associated with Hypercalcemia of Malignancy?
Kidney or Gallbladder stones, polyuria, bone pain, constipation & muscle weakness, depressed mood, confusion
What are the primary lab values associated with tumor lysis syndrome?
What is Hyperkalemia, Hyperphosphatemia, and Hyperuricemia?
BONUS: Is Calcium high or low with TLS?
What are two priority nursing considerations for a patient experiencing Leukostasis?
Ensuring TLS Protocol is in place (TLS Labs, allopurinol, fluids), symptom management (oxygen, antibiotics for fevers, monitor for bleeding), ensuring Hydroxyurea is ordered
>80% of hematologic malignancies and 10-50% of solid tumor patients will experience this Oncologic Emergency.
What is Febrile Neutropenia?
What is the diagnostic criteria for Febrile Neutropenia?
ANC <500 or ANC <1000 with expectation of being <500 at nadir AND Temperature >38.3 (101F) or >38 (100.4F) for 1 hour
What symptoms are associated with Cytokine Release Syndrome?
What is hypotension, hypoxia, and fever?
What three lab values are evaluated for Cytokine Release Syndrome?
What is LDH, C-reactive protein, and ferritin?
What are three management strategies used to relieve blockage and maintain vessel patency for a patient with Superior Vena Cava Syndrome?
Chemotherapy/radiation, Steroids – decrease inflammation, Analgesics and anxiolytics to relieve chest pain and anxiety, oxygen as indicated
What are two risk factors associated with tumor lysis syndrome?
What are large tumor burden (WBC > 100k, elevated LDH), cancers with high chemo sensitivity (leukemias, lymphomas), impaired renal function, and dehydration?