Antibiotics / Prophylaxis
Antibiotic agents should be administered within?
What is less than 66 minutes postinjury
Severe soft-tissue injury, contamination, and crushing; high-energy injury with comminution; wound size may be >10 cm.
What is GA III
Use of local antibiotic agents may _______ infection rates after high-risk open fracture without _______ systemic adverse?
What is decrease; increase
Studies have shown that saline with castile soap had ______ primary wound healing problems when compared to antibiotic solutions
what is decreased?
Risk of complications and or infection increases if soft-tissue coverage occurs?
How long is more than 5 to 7 days postinjury
If anaerobic infection is a substantial risk (farm injury) - what should ne added?
What is ampicillin or penicillin
Extensive soft-tissue injury with periosteal stripping and bony exposure
What is GA IIIB
vascular surgery consult and angiogram is warranted if ABI < ?
0.9
In open fractures, _________ bacteria are the most common infecting organisms?
Gram positive
Functional outcomes at 2 and 7 years between patients who underwent amputation versus limb salvage for severe open lower extremity injury?
What are similar outcomes; LEAP project
Tetanus prophylaxis complete but > 10 yr since last dose
What is recieve diphtheria and tetanus toxoids
Wound <1 cm in length; minimal contamination and soft-tissue damage; usually an inside-to-outside injury.
What is GA I
Low pressure bulb irrigation is less expensive than high pressure pulse lavage and has what effect on infection rates or union rates?
No difference
SHH Consult: Patient jumped into the ocean off their daddy's yacht and now their tibia is sticking out. What antibiotics do they need?
What are doxycycline + (ceftazidime or a fluoroquinolone)
Wounds in patients with an open fracture managed via NPWT are associated with?
What is lower rates of infection than wet to dry dressings
For freshwater or saltwater wounds what antibiotic should be added?
What is fluoroquinolone
Wound between 1 and 10 cm in length; soft-tissue injury and crushing are moderate; comminution is minimal.
What is GA II
Odds of infection in open tibial fractures increase by 16% for each day beyond day ?
What is day 7
Debridement for type IIIB open tibia fractures should occur?
How long is within 12 hours?
The capsule that forms around the spacer has been shown to result in the highest level of growth factors present at?
How long is 6 weeks
Antibiotic therapy is recommended for __ period of time after debridement?
How long is 24-72 hours
Any open fracture with an arterial injury requiring repair
What is GA IIIC
The flap used for a proximal 1/3 open tibial shaft fracture is perfused by?
What are the medial or lateral sural arteries?
A 29-year-old male sustained an open middle third tibial shaft fracture after a motocross accident, what is the best timing and flap selection for this patient?
Soleus, within 7 days
On contaminates surfaces, glycocalyx formation occurs within approximately?
How long is 6 hours postinjury.