Clinical Manifestations
Pathophysiology/Effects on organ systems
Diagnosis
Treatment
Miscellaneous
100

This phenomenon describes worsening of neurological symptoms with increased body temperature due to impaired nerve conduction.

Uhthoff’s phenomenon

100

This disease process involves the immune system mistakenly attacking components of the nervous systems.

Autoimmune response

100

Procedure that examines the depth of the layers within the eye, assessing for degradation of neurons.

Optical Coherence Tomography

100

This monoclonal antibody targets CD20 positive B cells and is used in progressive forms of the disease.

Ocrelizumab

100

Bands of immunoglobulins found in cerebrospinal fluid that support diagnosis of the disease

Oligoclonal bands

200

Some patients experience episodes of vision loss in one eye accompanied by pain during eye movement.

Optic neuritis

200

The primary target of immune damage in this disorder is the protective covering that surrounds nerve fibers.

Myelin

200

Test that measures electrical activity, and detects slowed nerve signals in brain, spinal cords, and nerves.

Evoked Potential Test

200

Medications that reduce inflammation, suppress the immune system, and increase recovery speed.

Eelapse Management Medications

200

Virus strongly associated with increased risk of developing the disease.

Epstein-Barr virus

300

Symptoms often come and go over time, reflecting a pattern of neurological deficits followed by partial recovery.

Relapsing-remitting symptoms

300

Damage leads to scattered areas of scar tissue forming throughout the brain and spinal cord.  

Plaques (lesions)

300

Procedure that collects cerebrospinal fluid in order to assess the proteins and other molecules in the fluid.

Spinal tap or cerebrospinal fluid test

300

Therapies that slow down disease development within the central nervous system.

Disease modifying therapies

300

This environmental factor, related to sunlight exposure, is thought to influence risk of developing the disease

Vitamin D

400

Patients frequently report muscle stiffness and involuntary spasms that affect movement and coordination.

Spasticity

400

This system is primarily affected, disrupting communication between the brain and the rest of the body.

Central nervous system

400

Primary Tool used to picture the brain and spinal cord.

MRI

400

Stimulation caused by electrical currents that improve the function of the specific lobe or portion in the brain.

Deep Brain Stimulation

400

Population more commonly affected by the disease.

Women

500

A very common complaint is persistent exhaustion that is not proportional to activity level.

Fatigue

500

Because of damage to nerve insulation, electrical signals slow down or fail to travel properly between neurons.

Impaired nerve conduction

500

Physician that diagnoses nervous system disruptions.

Neurologist

500

A form of therapy that helps people complete functional tasks after illness or injury.

Occupational therapy

500

This lifestyle habit is associated with faster disease progression.

Smoking

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