What is the ultimate goal of antiemetic therapy?
To minimize/prevent fluid and electrolyte disturbance and deterioration of pt's nutritional state
What are examples of antidopaminergic drugs?
Prochlorperazine and Promethazine
T/F: Serotonin Blockers are a Pregnancy Category B Drug.
True
What drugs are used as antibacterials for the skin?
Bacitracin, Neomycin and Polymyxin B (Neosporin), Mupirocin, Silver Sulfadiazine
Which drugs are used for wound care?
Vitamin C (ascorbic acid), zinc, soidum hypochlorite, cadexomer iodine, colalgenase, biafine topical emulsion
How do anticholinergic drugs such as Scopolamine treat nausea?
By binding to and blocking acetylcholine receptors
What do you need to watch out for when giving Promethazine IM?
Accidental intraarterial injection: can cause severe tissue damage! Stop therapy if burning/pain occurs!
What are examples of Serotonin Blockers?
Ondansetron, Granisetron, Dolasetron, Palonostron
Which drugs are used as antifungals?
Clotrimazole (for thrush) and Miconazole (for yeasts)
What are some skin prep drugs?
Isopropyl alcohol, povidone-iodine, chlorhexidine, benzalkonium chloride
What is the MOA for antihistamines related to nausea?
How do Neurokinin blockers work? Ex: Aprepitant
They inhibit substance P-neurokinin 1 receptors in the brain stem.
Which antinausea med class is used for pts being treated w. cancer and AIDS?
Tetrahydrocannabinoids
What drugs are antiacne drugs?
Benzoyl peroxide, clindamycin, isotretinoin, tretinoin
What drugs are used for IBS?
Tegaserod, Lubiprostone, Alosetron
What is Meclizine used for?
Dizziness, vertigo, nausea/vomiting and motion sickness.
What is Aprepitant used for?
How can tetrahydrocannabinoids benefit patients with AIDS?
it can stimulate appetite, which is common for wasting syndromes. Ex: Dronabinol
What is some pt teaching for Isotretinoin?
Avoid Vitamin A supplements, NO pregnancy - use 2 methods of contraceptive, avoid excessive sun, may cause dry eyes, risk for ICP (avoid tetracyclines)
What can ginger be used for?
Nausea
What are contraindications to Meclizine?
Shock and lactation
How do Prokinetic drugs work?
stimulates peristalsis in the GI tract (ex: metoclopramide)
What is Phosphorated Carbohydrate solution used for?
Morning sickness during pregnancy
What are examples of antipsoriatic drugs?
Tazarotene, tar-containing products, anthralin, calcipotriene
Which hair growth drug is a pregnancy category X drug?
Finasteride