Kidney Function & Failure
Hypertension
Angina & Myocardial Infarction
Adverse Effects & Contraindications
Prototype Drugs & Their Actions
100

This hormone, secreted by the kidneys, stimulates red blood cell production

erythropoietin

100

This system is the primary homeostatic mechanism for controlling blood pressure and involves renin, angiotensin, and aldosterone

the renin-angiotensin-aldosterone system

100

This prototype nitrate drug rapidly terminates angina pain by causing vasodilation of veins and coronary arteries.

Nitroglycerin

100

This adverse effect, characterized by swelling of the face, lips, tongue, or throat, can be life-threatening and is associated with ACE inhibitors.

Angioedema

100

This prototype ACE inhibitor is used to treat hypertension, heart failure, and to improve survival after myocardial infarction by blocking the conversion of angiotensin I to angiotensin II

Lisinopril

200

This is the best marker for estimating renal function, measuring the volume of filtrate passing through Bowman’s capsule per minute

glomerular filtration rate (GFR)?

200

This antihypertensive drug class works by inhibiting the conversion of angiotensin I to angiotensin II

ACE inhibitors

200

This beta blocker is a first-line medication for chronic angina pain and reduces cardiac workload by slowing heart rate.

Atenolol

200

This medication should never be taken with sildenafil due to the risk of life-threatening hypotension

nitroglycerin

200

This prototype ARB blocks angiotensin II from binding to its receptors, leading to vasodilation and is used to treat hypertension and protect kidney function in diabetic nephropathy

Losartan

300

This class of diuretics is most effective for rapid, severe fluid overload and works by blocking sodium and chloride reabsorption in the loop of Henle.

Loop Diuretics

300

This antihypertensive drug class blocks angiotensin II from binding to its receptors.

angiotensin II receptor blockers (ARBs)

300

This thrombolytic drug is used to dissolve clots in acute myocardial infarction by converting plasminogen to plasmin

Retaplase

300

This adverse effect, common with nitroglycerin use, is caused by cerebral vasodilation and can be severe enough to require discontinuation of the drug

Headache

300

This prototype alpha-1 adrenergic blocker is used to treat both hypertension and benign prostatic hyperplasia by relaxing vascular and prostate smooth muscle

Doxazosin

400

This diuretic class acts on the distal convoluted tubule to block sodium reabsorption and is commonly used to treat mild to moderate hypertension.

Thiazide Diuretics

400

This calcium channel blocker is used to treat hypertension and angina by causing vasodilation

nifedipine

400

This type of angina is characterized by chest pain that occurs more frequently, more intensely, and even at rest, and is considered a medical emergency

unstable angina

400

This calcium channel blocker is contraindicated in patients with severe hypotension, sick sinus syndrome without a pacemaker, or second- or third-degree AV block due to the risk of worsening bradycardia and heart failure.

diltiazem

400

This prototype direct-acting vasodilator is used for severe hypertension and hypertensive emergencies by causing rapid arterial smooth muscle relaxation

hydralazine

500

This diuretic class provides diuresis without affecting potassium levels by blocking aldosterone or sodium channels.

Potassium Sparing Diuretics

500

This antihypertensive drug is also used to treat benign prostatic hyperplasia by blocking alpha-1 receptors on vascular smooth muscle.

doxazosin

500

This sequence of medications, remembered by an acronym, is used in the initial management of a patient experiencing a myocardial infarction

MONA - Morphine, Oxygen, Nitroglycerin, and Aspirin

500

This drug is contraindicated in patients with active internal bleeding or a history of hemorrhagic stroke due to the risk of life-threatening bleeding

Reteplase

500

This prototype calcium channel blocker is used to treat hypertension and angina by causing vasodilation and reducing cardiac workload

Nifedipine

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