Intro to Pharmacology and Chemotherapeutics
This is the amount of time it takes for the concentration of drug in the blood to decrease by 50%.
What is half-life?
This powerful loop diuretic can be used to treat emergent pulmonary edema.
What is furosemide?
This opioid is an FDA-approved centrally-acting antitussive for dogs.
What is butorphanol?
Keratoconjunctivitis sicca, or KCS, is a known and potentially irreversible side effect of this class of antimicrobials.
What are sulfonamides?
What is mu?
This is the unit used to calculate chemotherapy (antineoplasitc) drug doses.
What is meters squared (or body surface area)?
This drug is an antiemetic and prokinetic.
What is metoclopramide?
This drug reduces thyroid hormone production by blocking use of iodine to make T3 and T4.
What is methimazole?
This is a powerful, highly nephrotoxic antifungal used to treat disseminated fungal disease.
What is amphotericin B?
This phenothiazine tranquilizer is know to cause hypotension, poor thermoregulation, prolapse of the third eyelid, and penile prolapse in stallions.
What is acepromazine?
This is the phenomenon by which the liver removes so much of the drug after absorption from the GI tract, that only a small fraction reaches systemic circulation.
What is first-pass effect?
This drug is categorized as an expectorant, but is used as a muscle relaxant in equine pre-anesthetic protocols.
What is guaifenesin?
This is a fast-acting inhalant beta-2 adrenergic agonist used to treat acute bronchoconstriction (i.e., due to asthma).
What is albuterol?
Penicillins, cephalosporins, and lincosamides are three classes of antibiotics are know to cause potentially fatal enterotoxemia in species known as (blank), especially if they are adminstered enterally.
What are hindgut fermenters?
This drug will reverse dexmedetomidine and other alpha-2 agonists.
What is atipamezole?
What is cyclophosphamide?
This sodium channel blocker is used to treat ventricular tachycardias and PVCs.
What is lidocaine?
This drug is a mucolytic and also an antidote for acetaminophen toxicosis.
What is acetylcysteine (or N-acetylcysteine)?
This is the mechanism of action for aminoglycosides, macrolides, and lincosamides.
What is disruption of ribosomal protein production?
This opioid is most likely to cause vasodilation due to histamine release when given as an IV bolus.
What is morphine?
This mechanism of repeated hepatic elimination into and reabsorption from the GI tract that prolongs the effects of drugs.
What is entero-hepatic circulation?
This calcium-channel blocker is used to treat systemic hypertension in cats with chronic kidney disease.
What is amlodipine?
This is why hypothyroid (dogs) are given the prodrug L-thyroxine (T4) instead of the active form, T3.
What is tissues can convert T4 to T3 as needed?
The mechanism of action for this class of antimicrobials is to interfere with normal DNA replication and function.
What are fluoroquinolones?
What is sevoflurane?