Learning and memory
Who was patient H.M.? What surgery did he have and what were the results of said surgery
Henry Gustav Molaison
He had a bilateral medial temporal lobectomy - removal of the temporal lobe
Partial seizure frequency decrease
Anti-convulsant meds decrease
No change in perceptual or motor abilities
Increase in Intelligence
What animal models of memory were discussed in class?
Object recognition memory: Delayed nonmatching to sample test (Monkeys), Mumby box (Rats)
Spatial recognition memory: Morris water maze, Radal arm maze
Define developmental disabilities
They are a group of conditions due to an impairment in physical learning, language, or behavior areas.
Compare and Contrast: Learning vs. Memory
Learning: the process of acquiring information
Memory: the ability to store and retrieve information
Define Sensory Buffers.
Fleeting memories/ glimpses of a scene that vanishes quickly.
Define dementia
Inability to remember, think or make decisons
Compare and contrast: Anterograde vd. Retrograde Amnesia
Anterograde: loss of memories formed after a brain injury
Retrograde: loss of memories formed before a brain injury
Define place cells
Neurons that respond when a subject is in a specific location in the test environment.
Define Autism Spectrum Disorder (According to the DMS)
Compare and contrast: Declarative vs. Non-declarative memory
Non-declarative: implicit memory (procedural memory)
Define Global Amnesia
Amnesia for information in all sensory modalities.
What were the types of associative learning that we discussed in class?
Classical conditioning:
Ivan Pavlov, Requires cerebellum, not hippocampus
Instrumental conditioning (operant conditioning)
B.F. Skinner, Reinforcement and punishment, No consistent brain region identified
Define Neuroplastisity
Changes in the structure and function of synapses that underlie learning and memory.