HLAs
This HLA is associated allopurinol hypersensitivity in Chinese, Thai, Korean and African American patients.
What is HLA-B*58:01 ?
This subtype of JIA with the highest risk of uveitis ?
What is oligoarticular JIA?
A fully humanized monoclonal antibody which blocks IL-6.
What is sarilumab?
This is a rare subacute variant of sarcoidosis characterized by parotid enlargement, fever, facial palsy and anterior uveitis.
What is Heerfordt-Waldenström syndrome?
This HLA is strongly associated with Behcet's disease.
HLA-B51
This genetic mutation is associated with familial Mediterranean fever?
What is MEVF gene?
Romosozumab is a monoclonal antibody which blocks this molecule.
What is sclerostin?
This syndrome is associated with livedo reticularis, cerebrovascular disease and antiphospholipid antibodies.
What is Sneddon's syndrome?
This HLA is associated with risk of rheumatoid arthritis.
What is HLADRB-1
Autoinflammatory disorder with positive NLRP3 genotype, urticarial rash and sensorineural hearing loss.
What is Muckle-Wells syndrome ?
This biologic was approved for psoriatic arthritis in 2022.
What is Risankizumab(Skyrizi) /
Autoinflammatory disorder manifested by granulomatous uveitis, dermatitis and arthritis.
What is Blau syndrome?
This HLA is associated with Birdshot chorioretinitis(uveiits).
What is HLA-A29 ?
This is the most common periodic fever syndrome.
What is PFAPA(Periodic fever with aphthous stomatitis, pharyngitis and adenitis syndrome)?
Antibody associated with inclusion body myositis.
What is anti-cytosolic 5’-nucleotidase 1A antibody?
This medication blocks preferentially JAK-1.
What is Upadacitinib?
This syndrome is characterized by branch retinal artery occlusions, sensorineural hearing loss, and subacute encephalopathy.
What is Susac syndrome?
HLA-Cw6 is associated with the early-onset of a disease.
What is psoriasis ?
Autoinflammatory disorder presenting with GI symptoms, cervical lymphadenitis, aphthous stomatitis and presence of MVK genotype? What is mevalonate kinase deficiency?
What is mevalonate kinase deficiency?
A slowly progressive neuromuscular disease characterized by muscle weakness and rod-shaped structures in muscle fibers associated with HIV.
What is nemaline (rod) myopathy?
IL-1 trap protein approved for the treatment of cryopyrin-associated periodic syndromes and recurrent pericarditis.
What is Rilonacept?
Adult-onset autoinflammatory disease caused by somatic mutations in ubiquitin activating enzyme 1 (UBA1) and manifested by systemic inflammation, cytopenias and dysplastic bone marrow with vacuolization of myeloid and erythroid precursor cells?
What is VEXAS(vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic) syndrome?