SIRS Criteria
Name two vital signs that are part of SIRS.
What is: Temp & HR (or RR)
Why is lactate measured?
To assess tissue hypoxia
Within how many hours should antibiotics be started?
1 hour
Pt: T 38.9, HR 112, BP 118/64, RR 22. Next action?
Get blood cultures, start fluids
SIRS from trauma — is this sepsis?
Not sepsis
What WBC count meets SIRS?
what is: >12,000 or <4,000
What lactate level requires urgent reassessment?
>4 mmol/L
How much fluid is given in initial resuscitation?
30 mL/kg crystalloid
Pt: lactate 5.2, MAP 58 after 2L fluids. Next?
Start norepinephrine
Fever, chills after transfusion. Is this sepsis?
No, transfusion reaction.
Does a patient meet SIRS if they have HR 94 and RR 24 but normal temp?
What is: YES
Name another important lab in sepsis besides lactate.
Blood cultures
How quickly should lactate be re-measured if initially elevated?
Within 2–4 hours
Pt: chills, confusion, O2 88%, RR 30. Priority?
Apply O2
Tachycardia from dehydration — SIRS?
Not sepsis
Why is SIRS important to recognize early?
What is: It may indicate sepsis risk
What imaging might be ordered in suspected pneumonia sepsis?
Chest X-ray
Why is it important to start fluids before vasopressors?
Corrects hypovolemia first
Pt: temp 36.0, WBC 2.8, on chemo. Concern?
Neutropenic sepsis
Pt: RR 24, anxiety, normal labs. Is this SIRS?
Not sepsis.
True or False: All SIRS patients are septic.
What is: FALSE
If creatinine is elevated, what might this indicate?
AKI from hypoperfusion
What is the MAP goal in septic shock?
≥65 mmHg
Pt: pancreatitis, HR 102, RR 24, WBC 14. Is this sepsis?
Not necessarily
Hypoxia from PE — sepsis?
Not sepsis.