Osteoarthritis & Fibromyalgia
How is osteoarthritis worked up/diagnosed?
CLINICAL DIAGNOSIS!!!
Imaging findings correlate poorly with the presence and severity of arthritis!! Only obtain XR or MRI if presentation is atypical for OA or if pain persists after a time-period of starting typical OA treatment.
Progressive destruction arthritis associated with loss of pain sensation &/or proprioception which subject joints to repeated trauma is called what?
Charcot joint
Most proven non-surgical treatment strategy for hip/knee osteoarthritis?
Weight loss
Name two of 3 diseases associated with pseudogout/CPPD?
Hyperparathyroidism, hypothyroidism, and hemochromatosis
Strongest risk factor for osteoarthritis?
Age
Name the disease that is associated with these symptoms:
Frontal bossing, large tongue, carpal tunnel, cranial nerve deficits(3,4,6), osteoarthritis, hypogonadism, cardiomegaly
Bonus point(+100): Most common cause of death in these patients?
Acromegaly
Bonus: Cardiomyopathy due to chronic GH and IGF-1 excess can cause cardiomyopathy, htn, arrhythmias, and LVH, which progressively impair heart function
What are the 2 bacteria that are commonly associated with Sickle Cell osteomyelitis
Staphylococcus Aureus
Salmonella
Explain the mechanism of hemophilic arthropathy from recurrent hemoarthrosis.
Iron-driven synovial inflammation and direct blood-mediated chondrocyte injury following recurrent hemarthrosis