Lumps
Bumps
Lesions
Spots
Margins and Resection
1
200 PTS
What is this?
Nevus Sebaceous (of Jadahsson)
1
300 PTS
Basal cell carcinoma is associated with overactivity of what pathway? What about SCC?
Basal cell: Sonic Hedgehog
SCC: P53
1
500 PTS
Differentiate Nevus of Ota and Nevus of Ito
Nevus of Ota: On face, preferentially involves areas innervated by V1 and V2
Nevus of Ito: On back, preferentially involves areas innervated by supraclavicular and brachiocutaneous nerves
1
300 PTS
What are the lesions on this patient's head? What syndrome are you suspicious of?
Multiple cylindromas, suspicious for Brooke-Spiegler Syndrome
1
300 PTS
Margins for BCC
If <2cm --> 4mm margins
If >2cm --> 10mm margins
2
100 PTS
What is the most common malignancy in Caucasians?
Basal Cell Carcinoma
2
100 PTS
What cutaneous malignancy are organ transplant recipients at highest risk for?
SCC
2
300 PTS
What topical medications can be used to treat basal cell carcinoma?
5FU or Imiquimod
2
500 PTS THAT YOU CAN STEAL FROM SOMEONE ELSE
Gorlin Syndrome
a) Name the mutation
b) Name 5 characteristics
PTCH1 mutation
a) Recurrent BCC
b) Palmar/plantar pitting
c) Odontogenic keratocysts
d) Bifid ribs
e) Macrocephaly
2
300 PTS
Melanoma of the fingers and toes requires what surgical treatment?
Amputation though the next phalanx proximal to the primary lesion
3
200 PTS
What is this? Be specific.
Nodular BCC
3
200 PTS
What is Bowen's disease?
SCC in situ
3
300 PTS
This lesion hurts a lot.
a) What are you suspicious of? (Full name!)
b) Is it malignant or benign?
Chondrodermatitis Nodularis Helicis
Benign
3
200 PTS
What are the ABCDEs that would cause a lesion to be suspicious for melanoma?
Asymmetry
Border irregularity
Color Variegation
Diameter >6mm
Evolution
3
300 PTS
When is a SLNB indicated during melanoma resection?
if lesion is > 1mm in thickness
4
200 PTS
What is this?
Keratoacanthoma
4
500 PTS
What are the 5 subtypes of basal cell carcinoma?
Nodular
Micronodular
Superficial Spreading
Morpheaform
Infiltrative
4
200 PTS
What is this suspicious for? Be specific.
Bonus 200 pts: What is the eponym for this sign?
Acral lentiginous melanoma
"Hutchinson's sign"
4
200 PTS
What are the two most significant prognostic factors associated with melanoma?
Ulceration and mitotic rate
4
300 PTS
Melanoma margins
In situ: 0.5cm
<1mm of depth: 1cm
1 to 4mm of depth: 2cm
>4mm: 2-3cm
5
200 PTS
What is the most aggressive subtype of BCC?
Morpheaform
5
300 PTS
What are the 5 subtypes of melanoma?
Nodular
Superficial spreading
Acral lentiginous
Desmoplastic
Lentigo maligna
5
200 PTS
How many cafe au lait macules warrants further workup? What is the further workup for?
>6 cafe au lait macules --> workup for NF1
5
500 PTS
Name any gene mutation linked to familial melanoma
CDK4
CDKN2A
MC1R
5
300 PTS
Margins for SCC
If <2cm, 4-6mm margins
If >2cm, 10mm margins