Variability in LRs
What are two and three person mixtures?
These describe the various properties of DNA behavior.
What are mass parameters?
This is the 'catch all' allele.
What is Q?
This type of artifact leads to inflation of the assumed number of contributors.
What is stutter?
This is what the acronym PCAST stands for.
What is the President's Council of Advisors on Science and Technology?
This method is the reason STRmix will not produce an identical answer after repeat interpretations.
What is Markov chain Monte Carlo (MCMC)?
STRmix uses this method to calculate an LR distribution.
What is the highest posterior density (HPD)?
Allelic product plus backstutter product gives you this.
What is total allelic product?
These contributing factors can make it difficult to determine the number of contributors.
What are peaks that may be artifacts, allelic, or both?
When the information present in a profile increases (by amount of DNA or fewer contributors) this is the result.
What is the power to discriminate contributors from non-contributors increases?
When the same sample is amplified repeatedly these factors can lead to variability across amplifications.
What are CE load injection variabilities and amplification?
The ability of the software to reliably resolve the DNA profile of known contributors within a mixed DNA profile for a range of DNA starting template.
What is sensitivity?
An iteration considers the following states.
What are the current state and a proposed state?
Peak heights will decrease as the molecular weight does this.
What is increase?
The overestimation of the NOC generally leads to [fill in blank] LRs for true contributors and an [fill in blank] increase in LRs for non-contributors.
What are lower and increase?
The magnitude of MCMC variation depends mainly on these two factors.
What are the size of the weights for genotype sets in Hp and the length the MCMC analysis is run?
This rate increases in situations where the true DNA donor is a close relative of the POI.
What is false inclusion?
What is the highest posterior density (HPD) method?
Inflating the number of contributors will do this to the LR of the major contributor.
What is nothing?
Mixtures with less DNA are not unreliable it's just that the are this.
What is less informative with respect to true and non-contributors?
Low level contributors typically have small weights in these types of samples.
What are mixtures?
This metaparameter describes the standard deviation of the normal distributions from which the step size for each continuous parameter is drawn.
What is the random walk standard deviation (RWSD)?
Allele mass can be effected by issues.
When expected stutter is similar in height to other alleles this happens to the LR of the minor contributor.
What is decrease?
False exclusions may be observed when one of these three things occurs.
What are (1) the reported NOC is < the true NOC, (2) human error, or (3) lack of allele separation during capillary electrophoresis?