Class Act
In the regimen DVRd, the "V" represents this drug.
What is bortezomib (Velcade)?
For transplant-ineligible patients, 1L typically involves these 2 phases of treatment.
What is induction and continuation?
The acronym BCMA stands for this.
What is B-cell maturation antigen?
This term describes a patient who has received a drug but did not progress on it.
What is exposed?
Daratumumab and isatuximab target this cell surface marker.
What is CD38?
With each successive line of therapy, attrition rates typically do this.
What is increase?
This modality delivers a cytotoxic payload directly to the myeloma cells via a targeted antibody.
What is an ADC?
Progression within this time window after stopping the treatment defines refractoriness
What is within 60 days?
This BsAb is currently administered as an IV infusion.
What is linvoseltamab?
In TE patients, the PERSEUS regimen is projected to reach this median PFS.
What is 17.1 years?
To improve availability, community practices are beginning to administer BsAb step-up dosing in this setting.
What is outpatient?
Triple-class refractory means the disease no longer responds to these major classes of therapy.
What are IMiDs, PIs, and anti-CD38 mAbs?