Diabetic Ketoacidosis
Criteria for DKA
What is:
1. Glucose ≥ 250
2. HCO3 ≥ 18
3. Anion gap > 12
4. pH < 7.3
5. beta-hydroxybutyrate ≥ 3.8
Associated with insulin deficiency
What is Type 1
“I want an Oompa-Loompa!' screamed Veruca.”
What is Charlie and the Chocolate Factory?
Recommended initial therapy for newly diagnosed T2DM
What is metformin?
Glucose goal for most inpatients per DCS
What is 140-180 mg/dL?
Three potential causes of DKA
What is:
1. Infection
2. Cardiovascular event
3. Cerebrovascular event
4. Medications
5. Substance use
6. Missed insulin
Associated with insulin resistance and insulin deficiency
What is type 2?
Love is like a bomb, baby, c'mon get it on
Livin' like a lover with a radar phone
Lookin' like a tramp, like a video vamp
Demolition woman, can I ___ _____ ____?
What is "be your man"
What is Pour Some Sugar on Me by Def Leppard
Two classes of glucose-lowering medications with evidence of cardiorenal benefit
What are GLP-1 agonists (the -glutides) and SGLT-2 inhibitors (the -flozins)?
Correction scale used for most patients having T1DM while inpatient
What is mild?
Three mainstays of treatment of DKA
What is:
1. IV fluids
2. IV insulin
3. potassium
Strongly associated with HLA DR3/4
What is Type 1?
1992 horror film set in Chicago's North Side; if you say his name 5 times to a mirror, he'll appear
What is Candyman?
Two classes of glucose-lowering medications that can help with weight loss
What are the GLP-1 agonists and SGLT2 inhibitors?
In DKA, the level of potassium at which you DON'T give any extra potassium
What is K+ greater than 5.2
When diabetic ketoacidosis is considered resolved
What is closure of the anion gap?
Strongly associated with acanthosis nigricans
What is type 2?
You talk about things that nobody cares
Wearing out things that nobody wears
You're calling my name but I gotta make clear
I can't say, baby, where I'll be ___ ___ ____
What is "in a year"
What is Sweet Emotion by Aerosmith
Glucose-lowering medication associated with the greatest expected decrease in A1c with monotherapy
What is insulin?
Can decrease A1c by 1.5-3.5 percentage points.
In DKA, frequency with which we check glucose until the anion gap closes
Q1H
One main difference between diabetic ketoacidosis and hyperosmolar hyperglycemia state
What is significant acidosis?
Significant acidosis or HCO3 greater than or equal to 16 is not present.
Strongly associated with ICA, IA-2 and ZnT8
What is type 1?
Chewy chocolate candy; also title of 1982 film in which Dustin Hoffman's character reinvents himself as "Dorothy Michaels" to get an acting job
What is Tootsie
The first glucagon-like peptide (GLP-1) receptor protein treatment approved for use in the United States that does not need to be injected
What is Rybelsus?
oral semaglutide
In DKA, the length of time that you continue IV insulin after subcutaneous insulin has been initiated
What is 1-2 hours