Side Effects
What is the E in ASLEEP mean?
Elevated heart rate or Extreme drop in BP
What should you take Trazodone with to reduce side effects of dizziness and lightheadedness
Food
What is the age for increased risk of suicidal thoughts?
Children, adolescents, and young adults (18-24)
What does Serotonin do to the body?
Its an antidepressant
What is the off label indication for Trazodone?
Insomnia
What does the S in ASLEEP mean?
sedation/somnolence
What should you avoid while taking Trazodone?
Driving or other activities requiring mental alertness or coordination.
Who should take caution in taking Trazodone?
Patient with seizures or family of seizures, brain damage, head trauma, or concurrent medications that may lower seizure threshold.
What does Histamine-1 do to the body?
Causes drowsiness
What is the brand name for trazodone
Desyrel
What does the P in ASLEEP mean?
Priapism? (rare)
What should you avoid while taking Trazodone?
Alcohol or other CNS depressants
How long do you have to wait to take trazodone if the use of MAO inhibitors?
14 days
What does Alpha-1 do to the body?
Causes hypotension
What is the abbreviation for the side effects of Trazodone?
ASLEEP
What does the L in ASLEEP mean?
Lightheadness/dizzy
Why should you rise slowly from sitting/laying down position?
Trazodone can cause Orthostatic hypotension
Who should take caution when using this drug?
people with seizures or a family of seizures, brain damage, head trauma, or concurrent medications that may lower seizure threshold
What is the MOA of trazodone?
Works by inhibiting the reuptake of serotonin but can also block histamine-1 receptors and alpha-1 adrenergic receptors
What should you avoid doing while taking trazodone?
Avoid driving or other activities requiring mental alertness or coordination
What does the A in ASLEEP mean?
Abdominal pain/nausea/vomiting/upset stomach
What is the risk higher in for orthostatic hypotension?
Elderly patients
What is contradicted with Trazodone?
linezolid or intravenous methylene blue
What does alpha-1 adrenergic receptors do?
Cause orthostasis
What can trazodone cause?
Drowsiness and sedation