indications
What is the main indication for Trazodone?
What is a black box warning for Trazodone?
Increased risk of suicidal thoughts in people 18-24 years old.
What is the mnemonic for Trazodone side effects?
What is Asleep.
What should be taken with food and why?
The immediate-release tablet should be taken with food to reduce dizziness and lightheadedness.
What is trazodones brand name?
What is Desyrel
What is an off label use for Trazodone?
What is Insomnia.
Patients with hypersensitivity to what medication are contraindicated when using Trazodone?
Patients with hypersensitivity to Trazodone or any component of its formulation.
What does the A stand for in the mnemonic?
What should a person avoid taking if they are using trazodone?
What is alcohol or any other CNS depressants.
What is a warning for trazodone?
What is avoiding driving or any activities that require mental alertness due to drowsiness/sedation.
What does MDD stand for?
What is trazodone contraindicated with?
Trazodone is contraindicated with the concurrent use of MAO inhibitors or within 14 days of discontinuation, or receiving linezolid or IV methylene blue.
What does the S stand for in the mnemonic?
What is Sedation/somnolence.
What should a person avoid doing when taking trazodone?
A person should avoid any activities requiring mental alertness.
What is the MOA for trazodone?
Trazodone inhibits the reuptake of serotonin but also blocks histamine-1 receptors and alpha-1 adrenergic receptors.
What is the main indication of Trazodone and the Off label use?
What is Major Depressive Disorder and Insomnia.
Why is trazodone contraindicated in patients with the concurrent use of MAO inhibitors or within 14 days of discontinuation, or receiving linezolid or IV methylene blue?
Combining these medications may lead to serotonin syndrome.
What does the L and P stand for in the mnemonic?
What is Lightheadedness/dizzy, and Priapism.
Why should a patient taking trazodone rise slowly from sitting/laying positions?
To prevent any falls due to orthostatic hypotension.
What is serotonin for when using trazodone?
What is an antidepressant.
What is the Insomnia?
A sleep disorder that causes difficulty falling asleep and staying asleep.
What patients should use caution when taking Trazodone?
Patients with seizure history, brain damage, head trauma, or concurrent medications that may lower seizure threshold.
What does both E's stand for in the mnemonic?
Extreme drop in BP(orthostatic Hypotension), and Elevated Heart rate.
What risk is higher for elderly patients when taking trazodone?
What is falling due to orthostatic hypotension.
What is Histamine-1 and Alpha-1 used for when taking trazodone?