Viral Therapy
The first human case of disease successfully treated with phages was what disease?
Dysentery
Significance of viruses are most apparent in this ecosystem:
Ocean
The existence of this virus has led to the hypothesis that viruses aren't non-living
Megaviruses
In 1919, D’Hérelle used phages targeting which host bacteria to cure typhoid outbreaks in Chickens
Salmonella
"Viruses are present in our oceans in such astronomical numbers, it's estimated that they would stretch from here past the next 60 ______ if laid end-to-end"
galaxies
What is of interest about the MyoAAV vectors/capsid variants?
"a family of capsids that zeroed in on muscle and mostly bypassed the liver"
Phages can be used to break up ______, enhancing antibiotic delivery and immune response.
Biofilm
Viruses (help) power ______, ______, _______ cycles
(These 3 chemical cycles)
Carbon, Nitrogen, Phosphorous
Name the processes that endogenous retroviral genes contributed to
placental processes / brain development / long-term memory formation / neuronal communication / influence immune function / embryonic development
GB virus C, an asymptomatic blood-borne virus reduces disease severity of these 2 diseases:
HIV, Ebola
Everyday, viruses in the ocean kill around __% of all marine bacteria.
20%
Viral vector-based gene therapies can cost up up to $_________ per treatment.
$2 million
2021, the U.S. FDA and the National Institute of Allergy and Infectious Diseases awarded $______ in grants to groups developing phage-based therapies.
2.5 million
All the dead bacteria lysed by viruses in the ocean release enough _____(not carbon) to support phytoplankton.
Iron
The only oncolytic virus approved in the United States, called T-VEC, is a modified type of what virus
Herpesvirus
This lab at Duke engineered a virus to differentially target and kill brain tumor cells
Gromeier
The Gromeier Lab at Duke uses an engineered form of this virus to target tumors
Poliovirus