DNA vs RNA
ENVELOPED vs NAKED
POSITIVE vs NEGATIVE SENSE RNA
FAMILY NAMES & HIGH-YIELD ASSOCIATIONS
BOARD-STYLE RESPIRATORY VIGNETTES
100

This common respiratory virus family includes adenovirus and contains double-stranded DNA.

What is Adenoviridae?

100

Influenza virus has this structural property, making it susceptible to soaps and detergents.

What is enveloped?

100

Influenza virus contains this type of RNA genome.

What is negative-sense single-stranded RNA (-ssRNA)?

100

RSV and parainfluenza belong to this viral family.

What is Paramyxoviridae?

100

A college student develops mild cough, rhinorrhea, and sore throat without fever. The causative virus is a naked positive-sense RNA Picornavirus. Identify the virus.

What is Rhinovirus?

200

Influenza, measles, RSV, and parainfluenza all belong to this broad viral genome category.

What are single-stranded RNA viruses?

200

This respiratory virus is notable for being naked and highly resistant to environmental conditions.

What is Adenovirus?

200

Rhinovirus and coronavirus are examples of this RNA polarity.

What is positive-sense RNA (+ssRNA)?

200

Rhinovirus belongs to this viral family.

What is Picornaviridae?

200

An infant presents with bronchiolitis and wheezing during winter. Chest x-ray shows hyperinflation. The virus forms multinucleated giant cells.

What is RSV?

300

This respiratory virus is a positive-sense RNA virus that caused the COVID-19 pandemic.

What is SARS-CoV-2?

300

Rhinovirus is structurally this type of virus.

What is a naked virus?

300

Measles, RSV, and parainfluenza all share this RNA genome orientation.

What is negative-sense RNA?

300

Coronavirus belongs to this viral family.

What is Coronaviridae?

300

A patient develops fever, cough, conjunctivitis, Koplik spots, and descending rash. The virus is an enveloped negative-sense RNA Paramyxovirus. Identify the virus.

What is Measles virus?

400

A virus causing bronchiolitis in infants is an enveloped negative-sense RNA virus in the Paramyxovirus family. Identify the virus.

What is Respiratory syncytial virus (RSV)?

400

A virus causing the common cold survives well on surfaces and spreads efficiently through fomites because it lacks this structure.

What is a viral envelope?

400

This positive-sense RNA respiratory virus belongs to the Picornavirus family and is the most common cause of the common cold.

What is Rhinovirus?

400

Influenza viruses belong to this viral family.

What is Orthomyxoviridae?

400

An elderly patient in a nursing home develops fever, myalgias, headache, and pneumonia during January. The virus possesses hemagglutinin and neuraminidase surface proteins.

What is Influenza virus?

500

A child develops conjunctivitis, pharyngitis, and pneumonia from a naked double-stranded DNA virus. Identify BOTH the virus and genome type.

What is Adenovirus, double-stranded DNA?

500

A daycare outbreak causes severe wheezing and bronchiolitis. The causative virus forms syncytia and is easily disrupted by alcohol sanitizer because of this structural property.

What is an envelope?

500

A patient develops fever, myalgias, and diffuse bilateral infiltrates during winter. The virus has a segmented negative-sense RNA genome and undergoes antigenic shift. Identify the virus.

What is Influenza virus?

500

A child presents with barking cough and inspiratory stridor. The causative virus belongs to the Paramyxovirus family and classically causes croup. Identify the virus.

What is Parainfluenza virus?

500

A hospitalized patient develops severe viral pneumonia with loss of taste and smell. The causative virus is an enveloped positive-sense RNA virus using spike proteins to bind ACE2 receptors. Identify the virus, family, and RNA polarity.

What is SARS-CoV-2, Coronaviridae, positive-sense RNA?

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