ATM deposit
Which gout medication must you always look for in serious rashes
Allopurinol
Most dangerous pregnancy dermatosis for baby
Intrahepatic cholestasis of pregnancy
Name any clinical presentation of Scleromyxedema
Papular mucinosis
Deep furrowing Shar-Pei sign
PIP joints donut sign depression with indurated rim
Leonine face
What percent of hair in anagen, catagen, and telogen
85-90%, 1%, 10%
What is koilonychia and cause
Spoon shape nails, iron deficiency
Gout looks like what on biopsy? Ideal liquid to put sample in to see uric acid crystals
Feathery. Ethanol (95%, or Carnoy’s fluid ethanol chloroform acetic acid)
Blood test (not skin related) to check during followup of pemphigoid gestationis and why
TSH Graves disease
3 causes of scleredema
Strep
IgG kappa monoclonal gammopathy
Diabetes
Name 3 features to look for on scalp alopecia biopsy
Hair density, follicle size, inflammation present, inflammation type, trichomalacia/pigment casts, fungi, scarring
Causes of Beau’s lines (name 2)
Trauma, systemic disease, chemo
Which syndrome has scapula white papules / pebbling
Hunter syndrome
Name all 3 essential features for atopic dermatitis
Pruritus
Eczematous morphology / location
Chronic or relapsing
Pathology biopsy - Difference between scleromyxedema and scleredema
Scleromyxedema triad fibroblasts, collagen, mucin
Scleredema increased mucin between collagen deep
Triad of Graham-Little-Piccardi-Lasseur syndrome
Scarring hair loss on scalp (LPP)
Non-scarring hair loss axilla and pubic area
KP spinous follicular papules
Yellow nail syndrome triad (yellow nails plus two others)
Yellow nails, pulmonary issue, lymphedema
3 types of cutaneous amyloid - clinical features and derived from what (keratin or light chains)
And how does systemic amyloid present on skin
Macular - flat rippled itchy back and upper arm, keratin
Lichen - raised rippled shins, back and extensors surfaces, itchy, keratin
Nodular - pink yellow nodule, light chains (7% progress to systemic amyloid)
Systemic - pinch purpura, macroglossia, waxy papulonodules (plasma cell dyscrasia)
Name 2 skin changes in pregnancy
Hyperpigmentation - areola, linea nigra, melasma
Hair - hirsutism, Telogen effluvium, Androgenetic alopecia
Nail - brittle, hyperkeratosis, onycholysis, transverse ridge
Glands - increased eccrine (except palms), increased sebaceous, decreased apocrine
Striae
Vascular - spider angioma, palmar erythema, edema, varicosities, purpura, gingival hyperplasia, Pyogenic granuloma, hemorrhoids
Reticular erythematous mucinosis similar to what other disease? Treatment?
Timid lupus, hydroxychloroquine
(Similar path to timid lupus too except DIF negative in REM)
Other than steroids, what is a key treatment to LPP and DLE scarring alopecia and why
Hydroxychloroquine, lymphocyte driven processes
Onycholysis vs onychomadesis appearance and name one cause of each
Onycholysis distal separation of nail plate from bed; psoriasis, fungal, trauma, doxy, tumor, hyperthyroid, pregnancy
Onychomadesis detached proximal nail plate from proximal nail fold; hand foot mouth disease, trauma, chemo, SJS/TEN, systemic illness, autoimmune
Lipoid proteinosis - gene, which other condition has same mutation, first finding in baby, classic skin finding, radiology
ECM1, lichen sclerosus, hoarse weak cry, string of pearls papules eyelid margin, temporal sickle shape calcifications
Also affects tongue, extensors, recurrent parotitis due to block salivary duct
Which of the four pregnancy dermatoses (pemphigoid gestationis, polymorphic eruption of pregnancy, atopic eruption of pregnancy, and intrahepatic cholestasis of pregnancy), hint more than one, commonly recur with subsequent pregnancy
pemphigoid gestationis
atopic eruption of pregnancy
intrahepatic cholestasis of pregnancy
Not PEP - unless multiple gestation (stretch skin)
How is scleromyxedema different than localized lichen myxedematosus (2 reasons)
Monoclonal gammopathy IgG lambda
Systemic involvement - myositis, CNS, peripheral neuropathy, pulm, cardiac, renal, GI
One med associated with hypertrichosis (other than minoxidil and steroids)
Which blistering condition has face hypertrichosis
One cause of acquired excess lanugo type hairs
Cyclosporine, phenytoin, prostaglandin (Latisse bimatoprost for eyelashes)
Porphyria cutanea tarda PCT
Anorexia (loss of fat, hair growth to insulate body), paraneoplastic
Mees lines vs Muerchkes lines (true vs transient leukonychia, location of nail that is affected, one cause)
Mees - true leukonychia, matrix, arsenic, trauma, meds, severe illness, psoriasis flare
Muerchke - transient/disappears with pressure, nail bed, low albumin, fluid overload